Evidence map›Paper›PMID 22926498›Full record

ArticleDigestive diseases and sciences2012

New paradigm for studying genetic contributions to irritable bowel syndrome.

Miranda A L van Tilburg, William E Whitehead

Abstract readEditorialComment
In one paragraph

Article in Digestive diseases and sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Miranda A L van Tilburg
William E Whitehead

Funding

Vulvar Vestibulitis syndrome (VVS)P01NS045685 · NINDS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ESSICK, GREGORY KENT · 2004 to 2014
$12.5M
PSYCHOPHYSIOLOGY OF IRRITABLE BOWEL SYNDROMER01DK031369 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WHITEHEAD, WILLIAM E · 1986 to 2012
$6.3M
NIDDK NIH HHS R01 DK031369NIDDK NIH HHS R01DK031369NINDS NIH HHS P01 NS045685NINDS NIH HHS P01NS045685
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene-Environment InteractionGenetic Predisposition to DiseasePolymorphism, GeneticFemaleHeterotrimeric GTP-Binding ProteinsHumansIrritable Bowel SyndromeMaleSerotonin Plasma Membrane Transport ProteinsG-protein beta3 subunitHeterotrimeric GTP-Binding ProteinsSerotonin Plasma Membrane Transport ProteinsSLC6A4 protein, human

Identifiers

PMID22926498
PMCPMC3468322

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.