ArticleMammalian genome : official journal of the International Mammalian Genome Society2012
Innovations in phenotyping of mouse models in the German Mouse Clinic.
Article in Mammalian genome : official journal of the International Mammalian Genome Society, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- Monoallelic variation in DHX9, the gene encoding the DExH-box helicase DHX9, underlies neurodevelopment disorders and Charcot-Marie-Tooth disease.American journal of human genetics · 2023Article
- New C3H KitScientific reports · 2022Article
- A comprehensive and comparative phenotypic analysis of the collaborative founder strains identifies new and known phenotypes.Mammalian genome : official journal of the International Mammalian Genome Society · 2020Article
- Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia.Experimental eye research · 2019Article
- Low catalytic activity is insufficient to induce disease pathology in triosephosphate isomerase deficiency.Journal of inherited metabolic disease · 2019Article
- Defective immuno- and thymoproteasome assembly causes severe immunodeficiency.Scientific reports · 2018Article
- Laboratory mouse housing conditions can be improved using common environmental enrichment without compromising data.PLoS biology · 2018Article
- Standardized, systemic phenotypic analysis reveals kidney dysfunction as main alteration of Kctd1Journal of biomedical science · 2017Article
- The First Scube3 Mutant Mouse Line with Pleiotropic Phenotypic Alterations.G3 (Bethesda, Md.) · 2016Article
- Viable EdnraMammalian genome : official journal of the International Mammalian Genome Society · 2016Article
- INFRAFRONTIER: a European resource for studying the functional basis of human disease.Mammalian genome : official journal of the International Mammalian Genome Society · 2016Review
- Discovery and characterization of spontaneous mouse models of craniofacial dysmorphology.Developmental biology · 2016Article
- Generation and Standardized, Systemic Phenotypic Analysis of Pou3f3L423P Mutant Mice.PloS one · 2016Article
- Clinical Chemistry Reference Intervals for C57BL/6J, C57BL/6N, and C3HeB/FeJ Mice (Mus musculus).Journal of the American Association for Laboratory Animal Science : JAALAS · 2016Article
- Network Modules of the Cross-Species Genotype-Phenotype Map Reflect the Clinical Severity of Human Diseases.PloS one · 2015Article
- Article
- Peroxidasin is essential for eye development in the mouse.Human molecular genetics · 2014Article
- Standardized, systemic phenotypic analysis of Slc12a1I299F mutant mice.Journal of biomedical science · 2014Article
- Retinal proteome alterations in a mouse model of type 2 diabetes.Diabetologia · 2014Article
- A robust and reliable non-invasive test for stress responsivity in mice.Frontiers in behavioral neuroscience · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
71 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Under the label of the German Mouse Clinic (GMC), a concept has been developed and implemented that allows the better understanding of human diseases on the pathophysiological and molecular level. This includes better understanding of the crosstalk between different organs, pleiotropy of genes, and the systemic impact of envirotypes and drugs. In the GMC, experts from various fields of mouse genetics and physiology, in close collaboration with clinicians, work side by side under one roof. The GMC is an open-access platform for the scientific community by providing phenotypic analysis in bilateral collaborations ("bottom-up projects") and as a partner and driver in international large-scale biology projects ("top-down projects"). Furthermore, technology development is a major topic in the GMC. Innovative techniques for primary and secondary screens are developed and implemented into the phenotyping pipelines (e.g., detection of volatile organic compounds, VOCs).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.