ArticlePediatrics2012
Bone mineral density and vitamin D status among African American children with forearm fractures.
Article in Pediatrics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.
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Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Vitamin D level and fractures in children and adolescents: a systematic review and meta-analysis.Journal of bone and mineral metabolism · 2021Pooled it
- Association of serum 25(OH)Vit-D levels with risk of pediatric fractures: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021Pooled it
- Vitamin D status among Thai school children and the association with 1,25-Dihydroxyvitamin D and parathyroid hormone levels.PloS one · 2014Trial
- Article
- The effect of vitamin D on the speed and quality of pediatric fracture healing.Journal of children's orthopaedics · 2025Article
- Vitamin D Levels During Fracture Healing in Children.Physiological research · 2024Article
- The role of bone health in low-velocity fractures and the effects of obesity on the growing skeleton.Journal of the Pediatric Orthopaedic Society of North America · 2024Article
- Girl predominance in trampoline-related forearm shaft fractures and their increasing incidence since 2000.BMC musculoskeletal disorders · 2023Article
- Article
- Vitamin D and Forearm Fractures in Children Preliminary Findings: Risk Factors and Correlation between Low-Energy and High-Energy Fractures.Children (Basel, Switzerland) · 2022Article
- Comparison of 25-OH vitamin D levels between children with upper and those with lower extremity fractures: A prospective case-control study.Acta orthopaedica et traumatologica turcica · 2022Article
- High-dose vitamin D supplementation in pregnancy and 25(OH)D sufficiency in childhood reduce the risk of fractures and improve bone mineralization in childhood: Follow-up of a randomized clinical trial.EClinicalMedicine · 2022Article
- Prevalence of Vitamin D Deficiency in Children with Fractures: Before and during the COVID-19 Outbreak.International journal of clinical practice · 2022Article
- Retrospective study of patterns of vitamin D testing and status at a single institution paediatric orthopaedics and sports clinics.BMJ open · 2021Article
- Calcium and vitamin D intake in allergic versus non-allergic children and corresponding parental attitudes towards dairy products.The World Allergy Organization journal · 2021Article
- High prevalence of vitamin D insufficiency in Chinese children with upper limb fractures.Genes & diseases · 2020Article
- A natural supplement formula reduces anti-oxidative stress and enhances osteo-chondrogenic differentiation potential in mesenchymal stem cells.Journal of clinical biochemistry and nutrition · 2020Article
- Consumption of Cow's Milk in Early Childhood and Fracture Risk: A Prospective Cohort Study.American journal of epidemiology · 2020Article
- Rachitic change and vitamin D status in young children with fractures.Skeletal radiology · 2020Observational
- Vitamin D levels and fracture risk among Hispanic children.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2019Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
objectiveTo determine whether African American children with forearm fractures have decreased bone mineral density and an increased prevalence of vitamin D deficiency (serum 25-hydroxyvitamin D level ≤ 20 ng/mL) compared with fracture-free control patients.
methodsThis case-control study in African American children, aged 5 to 9 years, included case patients with forearm fracture and control patients without fracture. Evaluation included measurement of bone mineral density and serum 25-hydroxyvitamin D level. Univariable and multivariable analyses were used to test for associations between fracture status and 2 measures of bone health (bone mineral density and 25-hydroxyvitamin D level) while controlling for other potential confounders.
resultsThe final sample included 76 case and 74 control patients. There were no significant differences between case and control patients in age, gender, parental education level, enrollment season, outdoor play time, height, or mean dietary calcium nutrient density. Cases were more likely than control patients to be overweight (49.3% vs 31.4%, P = .03). Compared with control patients, case patients had lower whole body z scores for bone mineral density (0.62 ± 0.96 vs 0.98 ± 1.09; adjusted odds ratio 0.38 [0.20-0.72]) and were more likely to be vitamin D deficient (47.1% vs 40.8%; adjusted odds ratio 3.46 [1.09-10.94]).
conclusionsThese data support an association of lower bone mineral density and vitamin D deficiency with increased odds of forearm fracture among African American children. Because suboptimal childhood bone health also negatively impacts adult bone health, interventions to increase bone mineral density and correct vitamin D deficiency are indicated in this population to provide short-term and long-term benefits.
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