Evidence map›Paper›PMID 22925897›Full record

Trial reportDer Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete2012

[Candida glabrata : pathogenicity and therapy update].

H-J Tietz

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Vulvar pruritus-Causes, Diagnosis and Therapeutic Approach.Deutsches Arzteblatt international · 2020
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

H-J TietzInstitut für Pilzkrankheiten und Mikrobiologie, Luisenstr. 50, 10117, Berlin, Deutschland. tietz@institut-fuer-pilzkrankheiten.de

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic recurrent vulvovaginal candidiasis caused by Candida glabrata is still rare in comparison to C. albicans infection, but therapy remains more difficult. Standard agents as fluconazole or itraconazole often fail, as well as the newer systemic triazoles like voriconazole or posaconazole. Micafungin is a new echinocandin drug with a wide antifungal spectrum including rare Candida species. No clinical trials with micafungin in chronic recurrent vulvovaginal candidiasis have been undertaken. We present the initial results employing a new therapy regimen consisting of micafungin in combination with topical ciclopirox olamine. All 14 patients with chronic recurrent vulvovaginal candidiasis caused by C. glabrata were treated successfully.

Indexed as

Administration, TopicalAntifungal AgentsCandida glabrataCandidiasis, CutaneousCandidiasis, VulvovaginalCiclopiroxDrug Therapy, CombinationEchinocandinsFemaleHumansLipopeptidesMicafunginPyridonesTreatment OutcomeAntifungal AgentsCiclopiroxEchinocandinsLipopeptidesMicafunginPyridones

Identifiers

PMID22925897
OpenAlexW112986772

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.