ArticleBMC plant biology2012
A naturally occurring InDel variation in BraA.FLC.b (BrFLC2) associated with flowering time variation in Brassica rapa.
Article in BMC plant biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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41 citing papers in PubMed, 100 citations in OpenAlex.
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- Non-vernalization requirement for flowering in Brassica rapa conferred by a dominant allele of FLOWERING LOCUS T.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- A 215-bp indel at intron I of BoFLC2 affects flowering time in Brassica oleracea var. capitata during vernalization.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
- Fine mapping and analysis of candidate genes for qFT7.1, a major quantitative trait locus controlling flowering time in Brassica rapa L.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
- A premature stop codon in BrFLC2 transcript results in early flowering in oilseed-type Brassica rapa plants.Plant molecular biology · 2022Article
- Non-vernalization requirement in Chinese kale caused by loss of BoFLC and low expressions of its paralogs.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
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- Their C-termini divideFrontiers in plant science · 2022Article
- Building a foundation for gene family analysis in Rosaceae genomes with a novel workflow: A case study inFrontiers in plant science · 2022Article
- A single amino acid residue substitution in BraA04g017190.3C, a histone methyltransferase, results in premature bolting in Chinese cabbage (Brassica rapa L. ssp. Pekinensis).BMC plant biology · 2021Article
- Impacts of allopolyploidization and structural variation on intraspecific diversification in Brassica rapa.Genome biology · 2021Article
- Assembly of the non-heading pak choi genome and comparison with the genomes of heading Chinese cabbage and the oilseed yellow sarson.Plant biotechnology journal · 2021Article
- Total FLC transcript dynamics from divergent paralogue expression explains flowering diversity in Brassica napus.The New phytologist · 2021Article
- Comparative transcriptomics reveals desynchronisation of gene expression during the floral transition between Arabidopsis andQuantitative plant biology · 2021Article
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFlowering time is an important trait in Brassica rapa crops. FLOWERING LOCUS C (FLC) is a MADS-box transcription factor that acts as a potent repressor of flowering. Expression of FLC is silenced when plants are exposed to low temperature, which activates flowering. There are four copies of FLC in B. rapa. Analyses of different segregating populations have suggested that BraA.FLC.a (BrFLC1) and BraA.FLC.b (BrFLC2) play major roles in controlling flowering time in B. rapa.
resultsWe analyzed the BrFLC2 sequence in nine B. rapa accessions, and identified a 57-bp insertion/deletion (InDel) across exon 4 and intron 4 resulting in a non-functional allele. In total, three types of transcripts were identified for this mutated BrFLC2 allele. The InDel was used to develop a PCR-based marker, which was used to screen a collection of 159 B. rapa accessions. The deletion genotype was present only in oil-type B. rapa, including ssp. oleifera and ssp. tricolaris, and not in other subspecies. The deletion genotype was significantly correlated with variation in flowering time. In contrast, the reported splicing site variation in BrFLC1, which also leads to a non-functional locus, was detected but not correlated with variation in flowering time in oil-type B. rapa, although it was correlated with variation in flowering time in vegetable-type B. rapa.
conclusionsOur results suggest that the naturally occurring deletion mutation across exon 4 and intron 4 in BrFLC2 gene contributes greatly to variation in flowering time in oil-type B. rapa. The observed different relationship between BrFLC1 or BrFLC2 and flowering time variation indicates that the control of flowering time has evolved separately between oil-type and vegetable-type B. rapa groups.
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