Trial reportNutrition journal2012
Body composition, dietary composition, and components of metabolic syndrome in overweight and obese adults after a 12-week trial on dietary treatments focused on portion control, energy density, or glycemic index.
Trial report in Nutrition journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 6 syntheses or guidelines pooled it, 67 citations in OpenAlex.
- Low-carbohydrate versus balanced-carbohydrate diets for reducing weight and cardiovascular risk.The Cochrane database of systematic reviews · 2022Pooled it
- A systematic review of the use of dietary self-monitoring in behavioural weight loss interventions: delivery, intensity and effectiveness.Public health nutrition · 2021Pooled it
- Protein Intake Greater than the RDA Differentially Influences Whole-Body Lean Mass Responses to Purposeful Catabolic and Anabolic Stressors: A Systematic Review and Meta-analysis.Advances in nutrition (Bethesda, Md.) · 2020Pooled it
- Low glycaemic index diets for the prevention of cardiovascular disease.The Cochrane database of systematic reviews · 2017Pooled it
- Effects of Popular Diets without Specific Calorie Targets on Weight Loss Outcomes: Systematic Review of Findings from Clinical Trials.Nutrients · 2017Pooled it
- Effects of dietary restriction on adipose mass and biomarkers of healthy aging in human.Aging · 2016Pooled it
- Similar body composition outcomes following volumetric diet and time-restricted eating in middle-aged individuals: a 12-week randomized controlled trial.Nutrition journal · 2025Trial
- Efficacy of a 3-month lifestyle intervention program using a Japanese-style healthy plate on body weight in overweight and obese diabetic Japanese subjects: a randomized controlled trial.Nutrition journal · 2014Trial
- Evaluating home-delivered meal service programs for obesity: a randomized controlled approach.Food & nutrition research · 2026Article
- Effects of low glycemic index/load diets on metabolic and inflammatory markers in humans: a meta-analysis.Frontiers in nutrition · 2026Article
- Effects of very low-calorie ketogenic diet on hypothalamic-pituitary-adrenal axis and renin-angiotensin-aldosterone system.Journal of endocrinological investigation · 2023Review
- Low glycaemic index or low glycaemic load diets for people with overweight or obesity.The Cochrane database of systematic reviews · 2023Review
- Optimising blood glucose control with portioned meal box in type 2 diabetes mellitus patients: a randomised control trial.Frontiers in nutrition · 2023Article
- Utilising a Real-Time Continuous Glucose Monitor as Part of a Low Glycaemic Index and Load Diet and Determining Its Effect on Improving Dietary Intake, Body Composition and Metabolic Parameters of Overweight and Obese Young Adults: A Randomised Controlled Trial.Foods (Basel, Switzerland) · 2022Article
- Consumption of energy-dense diets in relation to metabolic syndrome and inflammatory markers in Iranian female nurses.Public health nutrition · 2017Article
- Relationship between Added Sugars Consumption and Chronic Disease Risk Factors: Current Understanding.Nutrients · 2016Review
- Added sugars and risk factors for obesity, diabetes and heart disease.International journal of obesity (2005) · 2016Review
- Effect of Low Glycemic Index Diet Versus Metformin on Metabolic Syndrome.International journal of endocrinology and metabolism · 2015Article
- Investigation of relationship of visceral body fat and inflammatory markers with metabolic syndrome and its components among apparently healthy individuals.International journal of clinical and experimental medicine · 2015Article
- Dietary strategies to reduce metabolic syndrome.Reviews in endocrine & metabolic disorders · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGiven the rise in obesity and associated chronic diseases, it is critical to determine optimal weight management approaches that will also improve dietary composition and chronic disease risk factors. Few studies have examined all these weight, diet, and disease risk variables in subjects participating in recommended multi-disciplinary weight loss programs using different dietary strategies.
methodsThis study compared effects of three dietary approaches to weight loss on body composition, dietary composition and risk factors for metabolic syndrome (MetS). In a 12-week trial, sedentary but otherwise healthy overweight and obese adults (19 M & 138 F; 38.7±6.7 y; BMI 31.8±2.2) who were attending weekly group sessions for weight loss followed either portion control, low energy density, or low glycemic index diet plans. At baseline and 12 weeks, measures included anthropometrics, body composition, 3-day food diaries, blood pressure, total lipid profile, HOMA, C-reactive protein, and fasting blood glucose and insulin. Data were analyzed by repeated measures analysis of variance.
resultsAll groups significantly reduced body weight and showed significant improvements in body composition (p<0.001), and components of metabolic syndrome (p<0.027 to 0.002), although HDL decreased (p<0.001). Dietary energy, %fat and %saturated fat decreased while protein intake increased significantly (p<0.001). There were no significant differences among the three groups in any variable related to body composition, dietary composition, or MetS components.
conclusionDifferent dietary approaches based on portion control, low energy density, or low glycemic index produced similar, significant short-term improvements in body composition, diet compositin, and MetS components in overweight and obese adults undergoing weekly weight loss meetings. This may allow for flexibility in options for dietary counseling based on patient preference.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.