ReviewMicrobial cell factories2012
A comprehensive and quantitative review of dark fermentative biohydrogen production.
Review in Microbial cell factories, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed.
- Synergistic pre‑treatment-driven dark fermentation of domestic organic waste for high‑yield biohydrogen production.Folia microbiologica · 2026Article
- Redox-centric metabolic rewiring for dark-fermentative hydrogen production in Enterobacter aerogenes.Bioprocess and biosystems engineering · 2026Article
- Rerouting reductant flux via protein tethering enhances biohydrogen production in Thermococcus kodakarensis.Applied microbiology and biotechnology · 2026Article
- Electrifying waste: Lebanese olive cake as novel bioenergy substrate in microbial fuel cells.World journal of microbiology & biotechnology · 2025Article
- Biomanufacturing of hydrogen from waste molasses: A full-scale application.Environmental science and ecotechnology · 2025Article
- Optimization of hydrogen production in Enterobacter aerogenes by Complex I peripheral fragments destruction and maeA overexpression.Microbial cell factories · 2023Article
- Debottlenecking the biological hydrogen production pathway of dark fermentation: insight into the impact of strain improvement.Microbial cell factories · 2022Review
- Formate-driven HBiotechnology for biofuels and bioproducts · 2022Article
- Article
- Zeolite addition to improve biohydrogen production from dark fermentation of C5/C6-sugars and Sargassum sp. biomass.Scientific reports · 2021Article
- Woody biomass as a potential feedstock for fermentative gaseous biofuel production.World journal of microbiology & biotechnology · 2021Review
- Homologous production, one-step purification, and proof of NaBiotechnology for biofuels · 2020Article
- On-line analysis and in situ pH monitoring of mixed acid fermentation by Escherichia coli using combined FTIR and Raman techniques.Analytical and bioanalytical chemistry · 2020Article
- Overcoming Energetic Barriers in Acetogenic C1 Conversion.Frontiers in bioengineering and biotechnology · 2020Review
- Methods for quantification of growth and productivity in anaerobic microbiology and biotechnology.Folia microbiologica · 2019Review
- Metabolic reconstruction and experimental verification of glucose utilization in Desulfurococcus amylolyticus DSM 16532.Folia microbiologica · 2018Article
- Complex Multimeric [FeFe] Hydrogenases: Biochemistry, Physiology and New Opportunities for the Hydrogen Economy.Frontiers in microbiology · 2018Review
- Efficient whole cell biocatalyst for formate-based hydrogen production.Biotechnology for biofuels · 2018Article
- Microalgal cultivation for value-added products: a critical enviro-economical assessment.3 Biotech · 2017Review
- Co-production of hydrogen and ethanol from glucose inBiotechnology for biofuels · 2017Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biohydrogen production (BHP) can be achieved by direct or indirect biophotolysis, photo-fermentation and dark fermentation, whereof only the latter does not require the input of light energy. Our motivation to compile this review was to quantify and comprehensively report strains and process performance of dark fermentative BHP. This review summarizes the work done on pure and defined co-culture dark fermentative BHP since the year 1901. Qualitative growth characteristics and quantitative normalized results of H2 production for more than 2000 conditions are presented in a normalized and therefore comparable format to the scientific community.Statistically based evidence shows that thermophilic strains comprise high substrate conversion efficiency, but mesophilic strains achieve high volumetric productivity. Moreover, microbes of Thermoanaerobacterales (Family III) have to be preferred when aiming to achieve high substrate conversion efficiency in comparison to the families Clostridiaceae and Enterobacteriaceae. The limited number of results available on dark fermentative BHP from fed-batch cultivations indicates the yet underestimated potential of this bioprocessing application. A Design of Experiments strategy should be preferred for efficient bioprocess development and optimization of BHP aiming at improving medium, cultivation conditions and revealing inhibitory effects. This will enable comparing and optimizing strains and processes independent of initial conditions and scale.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.