Evidence map›Paper›PMID 22925064›Full record

ArticleJournal of forensic sciences2013

Characterization of the standard and recommended CODIS markers.

Sara H Katsanis, Jennifer K Wagner

Abstract read
In one paragraph

Article in Journal of forensic sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Associations between forensic loci and expression levels of neighboring genes may compromise medical privacy.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  8. Using DNA to reunify separated migrant families.Science (New York, N.Y.) · 2021
    Article
  9. Review
  10. Article
  11. Article
  12. Linkage disequilibrium matches forensic genetic records to disjoint genomic marker sets.Proceedings of the National Academy of Sciences of the United States of America · 2017
    Article
  13. The future of forensic DNA analysis.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2015
    Review
  14. Article
  15. Out with the "junk DNA" phrase.Journal of forensic sciences · 2013
    Article
  16. Two DifferentCancer genomics & proteomics
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sara H KatsanisGenome Ethics, Law & Policy, Duke Institute for Genome Sciences & Policy, Duke University, 304 Research Drive, Box 90141, Durham, NC 27708, USA. sara.katsanis@duke.edu
Jennifer K Wagner

Funding

Penn Center for ELSI Research in Emerging Genetic Technologies in Health CareP50HG004487 · NHGRI · UNIVERSITY OF PENNSYLVANIA · PI PYERITZ, REED E · 2007 to 2012
$6.2M
NHGRI NIH HHS P50 HG004487NHGRI NIH HHS P50HG004487-05
6 · The paper itself

Abstract

As U.S. courts grapple with constitutional challenges to DNA identification applications, judges are resting legal decisions on the fingerprint analogy, questioning whether the information from a DNA profile could, in light of scientific advances, reveal biomedically relevant information. While CODIS loci were selected largely because they lack phenotypic associations, how this criterion was assessed is unclear. To clarify their phenotypic relevance, we describe the standard and recommended CODIS markers within the context of what is known currently about the genome. We characterize the genomic regions and phenotypic associations of the 24 standard and suggested CODIS markers. None of the markers are within exons, although 12 are intragenic. No CODIS genotypes are associated with known phenotypes. This study provides clarification of the genomic significance of the key identification markers and supports--independent of the forensic scientific community--that the CODIS profiles provide identification but not sensitive or biomedically relevant information.

Indexed as

Databases, GeneticDNA FingerprintingGenetic MarkersForensic GeneticsGenetic LociGenotypeHumansIntronsMicrosatellite RepeatsMutationPhenotypePolymorphism, Single NucleotideGenetic Markers

Identifiers

PMID22925064
PMCPMC8591976

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.