Evidence map›Paper›PMID 22924431›Full record

Trial reportDevelopmental medicine and child neurology2012

Acceptability and potential effectiveness of a foot drop stimulator in children and adolescents with cerebral palsy.

Laura A Prosser, Lindsey A Curatalo, Katharine E Alter, Diane L Damiano

2 registry-linked trialsOpen access · bronzeAbstract readClinical Trial
In one paragraph

Trial report in Developmental medicine and child neurology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02462018 phase4unknown statusnot on this mapstarted 2015, after this paper: background citation

Effects of Functional Electrical Stimulation on Gait in Children With Hemiplegic and Diplegic Cerebral Palsy

TypeinterventionalSponsorTel-Aviv Sourasky Medical CenterRan2015 to 2017Enrolled20ConditionsCerebral Palsy, Congenital, Muscle SpasticityArmsWalkAide
NCT03016923 nacompletednot on this mapstarted 2016, after this paper: background citation

An Evaluation of the Effectiveness of Functional Electrical Stimulation Paired With Intensive Therapy to Improve Hand Function in Children With Hemiplegic Cerebral Palsy

TypeinterventionalSponsorHolland Bloorview Kids Rehabilitation HospitalRan2016 to 2017Enrolled3ConditionsCerebral PalsyArmsFES Therapy
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Review
  6. The Determination of Assistance-as-Needed Support by an Ankle-Foot Orthosis for Patients with Foot Drop.International journal of environmental research and public health · 2023
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Advances in neuroprosthetic management of foot drop: a review.Journal of neuroengineering and rehabilitation · 2020
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Laura A ProsserCenter for Rehabilitation, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Lindsey A Curatalo
Katharine E Alter
Diane L Damiano
National Institutes of Health · USChildren's Hospital of Philadelphia · USMt. Washington Pediatric Hospital · US

Funding

A Rigid Body Database On Human MovementZIACL060017 · CLC · CLINICAL CENTER · PI ALTER, KATHARINE · 2009 to 2025
$0k
Intramural NIH HHS ZIA CL060017
6 · The paper itself

Abstract

aimAnkle-foot orthoses are the standard of care for foot drop in cerebral palsy (CP), but may overly constrain ankle movement and limit function in those with mild CP. Functional electrical stimulation (FES) may be a less restrictive and more effective alternative, but has rarely been used in CP. The primary objective of this study was to conduct the first trial in CP examining the acceptability and clinical effectiveness of a novel, commercially available device that delivers FES to stimulate ankle dorsiflexion.

methodTwenty-one individuals were enrolled (Gross Motor Function Classification System [GMFCS] levels I and II, mean age 13y 2mo). Gait analyses in FES and non-FES conditions were performed at two walking speeds over a 4 month period of device use. Measures included ankle kinematics and spatiotemporal variables. Differences between conditions were revealed using repeated measures multivariate analyses of variance.

resultsNineteen individuals (nine females, 10 males; mean age 12y 11mo, range 7y 5mo to 19y 11mo; 11 at GMFCS level I, eight at level II) completed the FES intervention, with all but one choosing to continue using FES beyond that phase. Average daily use was 5.6 hours (SD 2.3). Improved dorsiflexion was observed during swing (mean and peak) and at foot-floor contact, with partial preservation of ankle plantarflexion at toe-off when using the FES at self-selected and fast walking speeds. Gait speed was unchanged.

interpretationThis FES device was well accepted and effective for foot drop in those with mild gait impairments from CP.

Indexed as

AdolescentAdultBiomechanical PhenomenaCerebral PalsyChildElectric Stimulation TherapyFemaleFoot DiseasesFoot OrthosesGaitHumansMalePeroneal NerveSeverity of Illness IndexTime FactorsTreatment Outcome

Identifiers

PMID22924431
PMCPMC3465476
OpenAlexW2120309672

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.