Evidence map›Paper›PMID 22924156›Full record

ArticleCurrent obstetrics and gynecology reports2012

Insights into Assessing the Genetics of Endometriosis.

Nilufer Rahmioglu, Stacey A Missmer, Grant W Montgomery, Krina T Zondervan

Abstract read
In one paragraph

Article in Current obstetrics and gynecology reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Multigenerational endometriosis : consequence of fetal exposure to diethylstilbestrol ?Environmental health : a global access science source · 2021
    Article
  10. Review
  11. Association between Single Nucleotide Polymorphisms and Endometriosis in a Brazilian Population.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2020
    Article
  12. Review
  13. Endometriosis.Endocrine reviews · 2019
    Review
  14. Article
  15. Endometriosis and nuclear receptors.Human reproduction update · 2019
    Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Common variation of theGenomics data · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nilufer Rahmioglu
Stacey A Missmer
Grant W Montgomery
Krina T Zondervan

Funding

Immunology, Inflammation, and EndometriosisR01HD057210 · NICHD · BRIGHAM AND WOMEN'S HOSPITAL · PI MISSMER, STACEY ANN · 2009 to 2012
$1.4M
Endogenous Hormones and Risk of EndometriosisR01HD052473 · NICHD · BRIGHAM AND WOMEN'S HOSPITAL · PI MISSMER, STACEY ANN · 2006 to 2009
$1.1M
NICHD NIH HHS R01 HD052473NICHD NIH HHS R01 HD057210Wellcome Trust 085235Wellcome Trust 090532
6 · The paper itself

Abstract

Endometriosis is a complex disease arising from the interplay between multiple genetic and environmental factors. The genetic variants potentially underlying the hereditary component of endometriosis have been widely investigated through hypothesis-driven candidate gene studies, an approach that generally has proven to be inherently difficult and problematic for a number of reasons. Recently, through major collaborative efforts in the endometriosis research field, hypothesis-free genome-wide approaches have started to provide new insights into potential pathways leading to development of endometriosis, as well as highlighting the phenotypic heterogeneity of the condition. This review summarizes the most recent studies investigating the genetic variation contributing to endometriosis, with a particular focus on genome-wide approaches, and discusses promising future directions of genetic research.

Identifiers

PMID22924156
PMCPMC3410033

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.