Evidence map›Paper›PMID 22923673›Full record

ArticleThe Plant cell2012

The shoot apical meristem regulatory peptide CLV3 does not activate innate immunity.

Cécile Segonzac, Zachary L Nimchuk, Martina Beck, Paul T Tarr, Silke Robatzek, Elliot M Meyerowitz, Cyril Zipfel

Abstract read
In one paragraph

Article in The Plant cell, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Review
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  8. Transcriptome dynamics atProceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  9. Plant peptides in plant defense responses.Plant signaling & behavior · 2018
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Cécile SegonzacThe Sainsbury Laboratory, Norwich Research Park, Norwich NR4 7UH, United Kingdom.
Zachary L Nimchuk
Martina Beck
Paul T Tarr
Silke Robatzek
Elliot M Meyerowitz
Cyril Zipfel

Funding

Role of the CLAVATA1 Receptor Kinase in Plant Stem Cell RegulationR01GM086639 · NIGMS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI MEYEROWITZ, ELLIOT M · 2008 to 2011
$1.3M
Biotechnology and Biological Sciences Research Council BB/E017134/1Biotechnology and Biological Sciences Research Council BB/G024944/1NIGMS NIH HHS 1R01GM086639NIGMS NIH HHS R01 GM086639
6 · The paper itself

Abstract

The Arabidopsis thaliana leucine-rich repeat receptor kinase FLAGELLIN SENSING2 (FLS2) is required for the recognition of bacterial flagellin in innate immunity. Recently, FLS2 was proposed to act as a multispecific receptor recognizing unrelated exogenous and endogenous peptide ligands, including CLAVATA3 (CLV3), a key regulator of shoot meristem stem cell production. Here, we report experimental evidence demonstrating that FLS2 does not recognize CLV3 and that the shoot apical meristem is immune to bacteria independently of CLV3 perception.

Indexed as

Plant ImmunityArabidopsisArabidopsis ProteinsEnzyme ActivationGreen Fluorescent ProteinsHost-Pathogen InteractionsLigandsMeristemPlant DiseasesPlants, Genetically ModifiedPlant ShootsProtein BindingProtein KinasesPseudomonas syringaeReceptors, Cell SurfaceArabidopsis ProteinsAT2G27250 protein, ArabidopsisFLS2 protein, ArabidopsisGreen Fluorescent ProteinsLigandsProtein KinasesReceptors, Cell Surface

Identifiers

PMID22923673
PMCPMC3462624

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.