ArticleBMJ open2012
Seasonality, incidence and prognosis in atrial fibrillation and stroke in Denmark and New Zealand.
Article in BMJ open, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Seasonal variation in the occurrence of ischemic stroke: A meta-analysis.Environmental geochemistry and health · 2019Pooled it
- Association of winter exposure with ischemic stroke risk in nonvalvular atrial fibrillation within a CHADS₂-based risk framework: a nationwide Japanese administrative claims database study.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2026Article
- Age-dependent seasonality in the incidence of stroke: A 21-year population-based study.European stroke journal · 2024Article
- Seasonality as a risk factor for deaths in Parkinson's disease.Clinics (Sao Paulo, Brazil) · 2024Article
- Seasonal variations in admissions for atrial fibrillation or atrial flutter in the Northeast and the Midwest regions of the United States.Proceedings (Baylor University. Medical Center) · 2024Article
- Seasonal Variation of Atrial Fibrillation Admission and Quality of Care in the United States.Journal of the American Heart Association · 2022Article
- Population's health information-seeking behaviors and geographic variations of stroke in Malaysia: an ecological correlation and time series study.Scientific reports · 2020Article
- Temperature and Precipitation Associate With Ischemic Stroke Outcomes in the United States.Journal of the American Heart Association · 2018Article
- Seasonal and Geographic Variation in Adverse Event Reporting.Drugs - real world outcomes · 2016Article
- Seasonal trends in sleep-disordered breathing: evidence from Internet search engine query data.Sleep & breathing = Schlaf & Atmung · 2015Article
- Modeling gradually changing seasonal variation in count data using state space models: a cohort study of hospitalization rates of stroke in atrial fibrillation patients in Denmark from 1977 to 2011.BMC medical research methodology · 2012Article
- Seasonal Variation in Paroxysmal Atrial Fibrillation: A Systematic Review.Journal of atrial fibrillationArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThere are relatively few large studies of seasonal variation in the occurrence of stroke in patients with atrial fibrillation (AF). We investigated the seasonal variation in incidence rates of hospitalisation with stroke in patients from Denmark and New Zealand.
designCohort study.
settingNationwide hospital discharge data from Denmark and New Zealand.
participants243 381 (median age 75) subjects having a first-time hospitalisation with AF in Denmark and 51 480 (median age 76) subjects in New Zealand constituted the study population. Subjects with previous hospitalisation with stroke were excluded. PRIMARY AND SECONDARY EFFECT MEASURES: Peak-to-trough ratio of the seasonal variation in incidence rates of stroke in AF patients adjusted for an overall trend was primary effect measure and was assessed using a log-linear Poisson regression model. Secondary effect measures were incidence rate ratios of AF and 30-day case fatality for stroke patients.
resultsIncidence rates of AF per 1000 person-years in Denmark increased by 5.4% (95% CI 5.3% to 5.7%) for patients aged <65 and 5% (95% CI 4.9% to 5.1%) for patients aged ≥65, whereas the increase was 0.2% (95% CI -0.2% to 0.6%) for patients aged <65 and 2.6% (95% CI 2.4% to 2.8%) for patients aged ≥65 in New Zealand. In Denmark 36 088 subjects were hospitalised with stroke, and 7518 subjects in New Zealand, both showing peaks during winter with peak-to-trough ratios of 1.22 and 1.27, respectively and a decreasing trend. The 30-day case fatality risk for stroke patients having AF is now (2000-2008) about 20% in both countries.
conclusionsAlthough incidence rates of hospitalisation with stroke in patients with AF have decreased in recent years, stroke remains a common AF complication with a high case fatality risk. The marked winter peak in incidence rates of hospitalisation with stroke in AF patients suggests that there are opportunities to reduce this complication. Further studies are necessary to identify how to optimise treatment of AF and prevention of stroke.
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