SynthesisEuropean child & adolescent psychiatry2013
Predictors and moderators of outcome in child and adolescent anxiety and depression: a systematic review of psychological treatment studies.
Synthesis in European child & adolescent psychiatry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- A systematic review of predictors and moderators of treatment response in psychological interventions for persisting forms of depression.The British journal of clinical psychology · 2025Pooled it
- Systematic review and meta-analysis of psychological interventions for depression symptoms in young people with long-term physical health conditions.Journal of pediatric psychology · 2025Pooled it
- A Meta-analysis to Guide the Enhancement of CBT for Childhood Anxiety: Exposure Over Anxiety Management.Clinical child and family psychology review · 2020Pooled it
- Preadolescent Benefits of Parent-Child Interaction Therapy Emotion Development for Preschool Depression: 4-Year Follow-Up.Journal of the American Academy of Child and Adolescent Psychiatry · 2026Trial
- Predictors and Moderators of Treatment Outcomes for Anxious Children Randomized to Computer-Assisted Cognitive Behavioral Therapy or Standard Community Care.Journal of child and adolescent psychopharmacology · 2023Trial
- Moderators of Response to Personalized and Standard Care Cognitive-Behavioral Therapy for Youth with Autism Spectrum Disorder and Comorbid Anxiety.Journal of autism and developmental disorders · 2022Trial
- Efficacy and Outcomes of a Music-Based Emotion Regulation Mobile App in Distressed Young People: Randomized Controlled Trial.JMIR mHealth and uHealth · 2019Trial
- Moving to Second-Stage Treatments Faster: Identifying Midtreatment Tailoring Variables for Youth with Anxiety Disorders.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53Trial
- Moving Beyond Moderation to Identify Differential Treatment Effects of Cognitive Behavioural Therapy for Childhood Anxiety: A Systematic Review.Clinical child and family psychology review · 2026Review
- The Electronic Psychiatric Semi-structured Interview for Children and Adolescents (EPSI-C): development and psychometric evaluation of an open-access DSM-5-based diagnostic instrument.Child and adolescent psychiatry and mental health · 2026Article
- Predictors of treatment outcomes in group cognitive behavioural therapy for orphaned adolescents in sheltered homes.Frontiers in psychiatry · 2026Article
- Who Benefits Most? Predictors of Treatment Response in Group Interventions for Children's Emotional Disorders.Child psychiatry and human development · 2025Article
- Social well-being moderates behavioral therapy response for generalized anxiety disorder.Journal of mood and anxiety disorders · 2025Article
- Adolescent psychiatric hospitalization: a naturalistic observational study of statistical and clinical outcomes and moderating factors.Child and adolescent psychiatry and mental health · 2025Article
- Treatment Outcomes of an Adolescent Intensive Outpatient Program for Depressed and Suicidal Youth.JAACAP open · 2025Article
- Who Benefits Most from Positive Psychological Interventions? Predictors and Moderators of Well-Being Outcomes in Severe Mental Health Conditions.Healthcare (Basel, Switzerland) · 2025Article
- Single-item patient-rated helpfulness and improvement as an alternative to standardized questionnaires for establishing anxiety and depression treatment efficacy.Psychological assessment · 2025Article
- Using Machine Learning to Predict Treatment Outcome in a Concatenated Dataset of Youth Anxiety Treatments.Child psychiatry and human development · 2025Article
- Association Between Early Childhood P300 Deficits and Risk for Preadolescence Depressive Disorder Mediated by Responsiveness to PCIT-ED Treatment.Research on child and adolescent psychopathology · 2025Article
- VIRTUS: virtual reality exposure training for adolescents with social anxiety - a randomized controlled trial.BMC psychiatry · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this literature review was to examine pre-treatment child and adolescent characteristics as predictors and moderators of outcome in psychotherapy treatment trials of anxiety and depressive disorders. A literature search was conducted using several databases and resulted in 45 published studies (32 anxiety studies and 13 depression studies) meeting predefined methodological criteria. Ten client demographic (age, gender, ethnicity, IQ) and clinical factors (duration, type of diagnosis, pre-treatment severity, comorbidity) were examined across studies. The majority of findings showed non-significant associations between demographic factors (gender and age) with treatment outcome for both the anxiety and the depression treatment trials. Some important differences between the results of the anxiety and depression treatment trials were found. The majority of findings for the anxiety studies suggest that there are no demographic or clinical factors that predict or moderate treatment outcome. For the depression studies, however, the findings suggest that baseline symptom severity and comorbid anxiety may impact on treatment response. Overall, existing studies of pre-treatment patient variables as predictors and moderators of anxiety and depression treatment outcome provide little consistent knowledge concerning for what type of patients and under what conditions treatments work. Suggestions for future research are discussed.
Indexed as
Identifiers
22923065What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.