ReviewThe Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry2013
The logic of inhibitory connectivity in the neocortex.
Review in The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers.
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Who cites it
98 citing papers in PubMed.
- Effects of spatial constraints of inhibitory connectivity on the dynamical development of criticality in spiking networks.PLoS computational biology · 2026Article
- Neuronal ensembles in cortical function and disease.Physiological reviews · 2026Review
- Cellular and subcellular specialization enables biology-constrained deep learning.Cell reports · 2026Article
- Modular inhibitory coding in binary networks.Frontiers in network physiology · 2026Article
- Neocortical somatostatin neuron diversity in cognition and learning.Trends in neurosciences · 2025Review
- Article
- The gamma rhythm as a guardian of brain health.eLife · 2024Review
- Electroacupuncture inhibited carrageenan-induced pain aversion by activating GABAergic neurons in the ACC.Molecular brain · 2024Article
- Molecular mechanisms underlying structural plasticity of electroconvulsive therapy in major depressive disorder.Brain imaging and behavior · 2024Article
- A latent pool of neurons silenced by sensory-evoked inhibition can be recruited to enhance perception.Neuron · 2024Article
- GABAergic synaptic scaling is triggered by changes in spiking activity rather than AMPA receptor activation.eLife · 2024Article
- Highly local activation of inhibition at the seizure wavefront in vivo.Cell reports · 2024Article
- Short-latency prepulse inhibition of the trigeminal blink reflex.Frontiers in neuroscience · 2024Article
- Serotonergic Modulation of the Excitation/Inhibition Balance in the Visual Cortex.International journal of molecular sciences · 2023Article
- Isochronic development of cortical synapses in primates and mice.Nature communications · 2023Article
- Article
- Article
- Unitary synaptic responses of parvalbumin interneurons evoked by excitatory neurons in the mouse barrel cortex.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Pharmacological Signature and Target Specificity of Inhibitory Circuits Formed by Martinotti Cells in the Mouse Barrel Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Reduced excitatory neuron activity and interneuron-type-specific deficits in a mouse model of Alzheimer's disease.Communications biology · 2022Article
38 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Although inhibition plays a major role in the function of the mammalian neocortex, the circuit connectivity of GABAergic interneurons has remained poorly understood. The authors review recent studies of the connections made to and from interneurons, highlighting the overarching principle of a high density of unspecific connections in inhibitory connectivity. Whereas specificity remains in the subcellular targeting of excitatory neurons by interneurons, the general strategy appears to be for interneurons to provide a global "blanket of inhibition" to nearby neurons. In the review, the authors highlight the fact that the function of interneurons, which remains elusive, will be informed by understanding the structure of their connectivity as well as the dynamics of inhibitory synaptic connections. In a last section, the authors describe briefly the link between dense inhibitory networks and different interneuron functions described in the neocortex.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.