Evidence map›Paper›PMID 22922199›Full record

ArticleJournal of biosciences2012

Metabolic response to exogenous ethanol in yeast: an in vivo statistical total correlation NMR spectroscopy approach.

Maso Ricci, Marianna Aggravi, Claudia Bonechi, Silvia Martini, Anna Maria Aloisi, Claudio Rossi

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of biosciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maso RicciDepartment of Pharmaceutical and Applied Chemistry, University of Siena, Siena, Italy. ricci2@unisi.it
Marianna Aggravi
Claudia Bonechi
Silvia Martini
Anna Maria Aloisi
Claudio Rossi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In vivo NMR spectroscopy, together with selectively 13C-labelled substrates and 'statistical total correlation spectroscopy' analysis (STOCSY), are valuable tools to collect and interpret the metabolic responses of a living organism to external stimuli. In this study, we applied this approach to evaluate the effects of increasing concentration of exogenous ethanol on the Saccharomyces cerevisiae fermentative metabolism. We show that the STOCSY analysis correctly identifies the different types of correlations among the enriched metabolites involved in the fermentation, and that these correlations are quite stable even in presence of a stressing factor such as the exogenous ethanol.

Indexed as

EthanolFermentationMagnetic Resonance SpectroscopyNuclear Magnetic Resonance, BiomolecularSaccharomyces cerevisiaeEthanol

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.