ReviewTrends in immunology2012
Heterogeneity in the differentiation and function of memory B cells.
Review in Trends in immunology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 69 citations in OpenAlex.
- Progressive deterioration of adaptive immune repertoires in Down syndrome linked to interferon hyperactivity and lymphoid tissue disorganization.bioRxiv : the preprint server for biology · 2026Article
- The multilayered identity of B cell memory.Cellular & molecular immunology · 2026Review
- Biometric Strategies to Improve Vaccine Immunogenicity and Effectiveness.Biomimetics (Basel, Switzerland) · 2025Review
- B cell memory: from generation to reactivation: a multipronged defense wall against pathogens.Cell death discovery · 2024Review
- Establishment of isotype-switched, antigen-specific B cells in multiple mucosal tissues using non-mucosal immunization.NPJ vaccines · 2023Article
- Heterogeneity of B cell lymphopoiesis in patients with premalignant and active myeloma.JCI insight · 2023Article
- Impaired antibody responses were observed in patients with type 2 diabetes mellitus after receiving the inactivated COVID-19 vaccines.Virology journal · 2023Article
- Bhlhe40 function in activated B and TFH cells restrains the GC reaction and prevents lymphomagenesis.The Journal of experimental medicine · 2022Article
- Limited access to antigen drives generation of early B cell memory while restraining the plasmablast response.Immunity · 2021Article
- High-dimensional mass cytometry identifies T cell and B cell signatures predicting reduced risk of Plasmodium vivax malaria.JCI insight · 2021Observational
- IgMParasitology · 2020Article
- Longitudinal dynamics of the human B cell response to the yellow fever 17D vaccine.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Evaluation of a ConvitVax/anti-PD-1 combined immunotherapy for breast cancer treatment.Oncotarget · 2019Article
- Decreased humoral immunity to mumps in young adults immunized with MMR vaccine in childhood.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Memory CD4European journal of immunology · 2019Article
- Atypical chemokine receptor 4 shapes activated B cell fate.The Journal of experimental medicine · 2018Article
- Accurate immune repertoire sequencing reveals malaria infection driven antibody lineage diversification in young children.Nature communications · 2017Article
- The transcription factor Runx3 guards cytotoxic CD8Nature immunology · 2017Article
- Mechanisms of Adaptive Immunity to Porcine Reproductive and Respiratory Syndrome Virus.Viruses · 2017Review
- The comparative immunology of wild and laboratory mice, Mus musculus domesticus.Nature communications · 2017Article
Corrections and comments
- Commented on by
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Vaccines that induce neutralizing antibodies have led to the eradication of small pox and have severely reduced the prevalence of many other infections. However, even the most successful vaccines do not induce protective antibodies in all individuals, and can fail to induce lifelong immunity. A key to remedying these shortcomings may lie in a better understanding of long-lived memory B cells. Recent studies have revealed novel insights into the differentiation and function of these cells, and have shown that the memory B cell pool is much more heterogeneous than previously appreciated.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.