ReviewEpigenomics2012
Epigenetics and childhood asthma: current evidence and future research directions.
Review in Epigenomics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 42 citations in OpenAlex.
- The H3K27me3-NR1D1-IFN-γ axis in trained macrophages induced by early respiratory virus infection drives non-T2 asthma in children.Cellular & molecular immunology · 2026Article
- Mechanisms and therapeutic strategies of asthma: from bench to bedside.Signal transduction and targeted therapy · 2026Review
- Dietary Acid Load Modulation of Asthma-Related miRNAs in the Exhaled Breath Condensate of Children.Nutrients · 2022Article
- Health and Well-Being Outcomes of Adolescents Conceived Through In Vitro Fertilization and Intracytoplasmic Sperm Injection.Reproductive sciences (Thousand Oaks, Calif.) · 2021Article
- Exposure to traffic-related air pollution and changes in exhaled nitric oxide and DNA methylation in arginase and nitric oxide synthase in children with asthma.Environmental health : a global access science source · 2021Article
- The Role of Short-Chain Fatty Acids in the Interplay between a Very Low-Calorie Ketogenic Diet and the Infant Gut Microbiota and Its Therapeutic Implications for Reducing Asthma.International journal of molecular sciences · 2020Review
- Children's Environmental Health: A Systems Approach for Anticipating Impacts from Chemicals.International journal of environmental research and public health · 2020Review
- Identification of Epigenetic Mechanisms Involved in the Anti-Asthmatic Effects ofMolecules (Basel, Switzerland) · 2018Article
- Air Pollution and the Epigenome: A Model Relationship for the Exploration of Toxicoepigenetics.Current opinion in toxicology · 2017Article
- DNA methylation-based variation between human populations.Molecular genetics and genomics : MGG · 2017Review
- Epigenetic regulation of Newborns' imprinted genes related to gestational growth: patterning by parental race/ethnicity and maternal socioeconomic status.Journal of epidemiology and community health · 2015Article
- Epigenetics of inflammation, maternal infection, and nutrition.The Journal of nutrition · 2015Review
- Beyond the genome: epigenetic mechanisms in lung remodeling.Physiology (Bethesda, Md.) · 2014Review
- Epigenetics of discordant monozygotic twins: implications for disease.Genome medicine · 2014Review
- Epigenetics in immune-mediated pulmonary diseases.Clinical reviews in allergy & immunology · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Asthma is the most common chronic disease of childhood, affecting one in eight children in the USA and worldwide. It is a complex disease, influenced by both environmental exposures and genetic factors. Although epigenetic modifications (DNA methylation, histone modification and miRNA) can affect transcriptional activity in multiple genetic pathways relevant for asthma development, very limited work has been carried out so far to examine the role of epigenetic variations on asthma development and management. This review provides a brief overview of epigenetic modifications, summarizes recent findings, and discusses some of the major methodological concerns that are relevant for asthma epigenetics.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.