ReviewFrontiers in cellular and infection microbiology2012
Cellular and physiological effects of anthrax exotoxin and its relevance to disease.
Review in Frontiers in cellular and infection microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 43 citations in OpenAlex.
- Trial
- Early Circulating Edema Factor in Inhalational Anthrax Infection: Does It Matter?Microorganisms · 2024Article
- Cancer Drug Delivery Systems Using Bacterial Toxin Translocation Mechanisms.Bioengineering (Basel, Switzerland) · 2023Review
- Some Peculiarities of Anthrax Epidemiology in Herbivorous and Carnivorous Animals.Life (Basel, Switzerland) · 2022Review
- A multipathogen DNA vaccine elicits protective immune responses against two class A bioterrorism agents, anthrax and botulism.Applied microbiology and biotechnology · 2022Article
- Recombinant full-lengthFrontiers in immunology · 2022Article
- Multiple stages of evolutionary change in anthrax toxin receptor expression in humans.Nature communications · 2021Article
- TheMicroorganisms · 2020Review
- Article
- Unique, Intersecting, and Overlapping Roles of C/EBP β and CREB in Cells of the Innate Immune System.Scientific reports · 2018Article
- Development of Protective Immunity in New Zealand White Rabbits Challenged with Bacillus anthracis Spores and Treated with Antibiotics and Obiltoxaximab, a Monoclonal Antibody against Protective Antigen.Antimicrobial agents and chemotherapy · 2018Article
- Review
- Soluble P-selectin rescues mice from anthrax lethal toxin-induced mortality through PSGL-1 pathway-mediated correction of hemostasis.Virulence · 2017Article
- Surviving Between Hosts: Sporulation and Transmission.Microbiology spectrum · 2016Review
- Raxibacumab augments hemodynamic support and improves outcomes during shock with B. anthracis edema toxin alone or together with lethal toxin in canines.Intensive care medicine experimental · 2015Article
- Anti-infective immunoadhesins from plants.Plant biotechnology journal · 2015Review
- Article
- New insights into gastrointestinal anthrax infection.Trends in molecular medicine · 2015Review
- Nitric oxide as a regulator of B. anthracis pathogenicity.Frontiers in microbiology · 2015Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Bacillus anthracis, the causative agent of anthrax, secretes a tri-partite exotoxin that exerts pleiotropic effects on the host. The purification of the exotoxin components, protective antigen, lethal factor, and edema factor allowed the rapid characterization of their physiologic effects on the host. As molecular biology matured, interest focused on the molecular mechanisms and cellular alterations induced by intoxication. Only recently have researchers begun to connect molecular and cellular knowledge back to the broader physiological effects of the exotoxin. This review focuses on the progress that has been made bridging molecular knowledge back to the exotoxin's physiological effects on the host.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.