Evidence map›Paper›PMID 22919650›Full record

ReviewFrontiers in cellular and infection microbiology2012

The influence of early neutrophil-Leishmania interactions on the host immune response to infection.

Flavia L Ribeiro-Gomes, David Sacks

Abstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

76 citing papers in PubMed.

  1. Article
  2. Review
  3. Hematological Ratios inAnimals : an open access journal from MDPI · 2026
    Article
  4. Article
  5. Frontiers in immunology · 2026
    Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Neutrophil-ACS infectious diseases · 2025
    Article
  11. Article
  12. Review
  13. Frontiers in immunology · 2024
    Article
  14. Article
  15. Article
  16. Leishmaniasis: Immune Cells Crosstalk in Macrophage Polarization.Tropical medicine and infectious disease · 2023
    Review
  17. Frontiers in immunology · 2023
    Article
  18. Elucidating the role played by bone marrow in visceral leishmaniasis.Frontiers in cellular and infection microbiology · 2023
    Review
  19. Article
  20. The History of Live AttenuatedPathogens (Basel, Switzerland) · 2022
    Review

16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Flavia L Ribeiro-GomesLaboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda MD, USA.
David Sacks

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neutrophils are the first cells recruited to the dermal site of Leishmania infection following injection by needle or sand fly bite. The role of neutrophils in either promoting or suppressing host immunity remains controversial. We discuss the events driving neutrophil recruitment, their interaction with the parasite and apoptotic fate, and the nature of their encounters with other innate cells. We suggest that the influence of the neutrophil response on infection outcome critically depends on the timing of their recruitment and the tissue environment in which it occurs.

Indexed as

Host-Pathogen InteractionsAnimalsHumansLeishmaniaLeishmaniasisNeutrophilsPsychodidaeSkinapoptosisdendritic cellsimmune responseinflammationLeishmaniamacrophagesneutrophilssand fly

Identifiers

PMID22919650
PMCPMC3417510

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.