Evidence map›Paper›PMID 22919625›Full record

ReviewFrontiers in cellular and infection microbiology2012

Staphylococcal response to oxidative stress.

Rosmarie Gaupp, Nagender Ledala, Greg A Somerville

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 118 papers.

0numbers the graph read from it
0cells of the map it votes in
118citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

118 citing papers in PubMed, 245 citations in OpenAlex.

  1. Trial
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  12. Review
  13. Base excision repair inFrontiers in microbiology · 2026
    Review
  14. Article
  15. Network analysis of antimicrobial resistance inNAR genomics and bioinformatics · 2025
    Article
  16. A ZnCommunications biology · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Nucleoid-associated proteins: molecular mechanisms in microbial adaptation.World journal of microbiology & biotechnology · 2025
    Review

58 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Rosmarie GauppSchool of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln NE, USA.
Nagender Ledala
Greg A Somerville
University of Nebraska–Lincoln · US

Funding

Citric acid cycle regulation of exopolysaccharide synthesis in staphylococciR01AI087668 · NIAID · UNIVERSITY OF NEBRASKA LINCOLN · PI SOMERVILLE, GREG ALAN · 2010 to 2013
$1.4M
NIAID NIH HHS R01 AI087668
6 · The paper itself

Abstract

Staphylococci are a versatile genus of bacteria that are capable of causing acute and chronic infections in diverse host species. The success of staphylococci as pathogens is due in part to their ability to mitigate endogenous and exogenous oxidative and nitrosative stress. Endogenous oxidative stress is a consequence of life in an aerobic environment; whereas, exogenous oxidative and nitrosative stress are often due to the bacteria's interaction with host immune systems. To overcome the deleterious effects of oxidative and nitrosative stress, staphylococci have evolved protection, detoxification, and repair mechanisms that are controlled by a network of regulators. In this review, we summarize the cellular targets of oxidative stress, the mechanisms by which staphylococci sense oxidative stress and damage, oxidative stress protection and repair mechanisms, and regulation of the oxidative stress response. When possible, special attention is given to how the oxidative stress defense mechanisms help staphylococci control oxidative stress in the host.

Indexed as

Oxidative StressStress, PhysiologicalAnimalsGene Expression Regulation, BacterialHumansMetabolic Networks and PathwaysStaphylococcusoxidative stressStaphylococcus

Identifiers

PMID22919625
PMCPMC3417528
OpenAlexW2057838384

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.