Evidence map›Paper›PMID 22919607›Full record

ReviewFrontiers in cellular and infection microbiology2012

Defense and adaptation: the complex inter-relationship between Campylobacter jejuni and mucus.

Abofu Alemka, Nicolae Corcionivoschi, Billy Bourke

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
5.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 66 citations in OpenAlex.

  1. Glycoconjugate diversification inbioRxiv : the preprint server for biology · 2026
    Article
  2. Consequences ofMicroorganisms · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Characterizing the Effect ofAnimals : an open access journal from MDPI · 2024
    Article
  7. Modulation ofFrontiers in cellular and infection microbiology · 2024
    Article
  8. Review
  9. Review
  10. Article
  11. Mucosal Environment Induces Phage Susceptibility inPHAGE (New Rochelle, N.Y.) · 2022
    Article
  12. Review
  13. Impact ofAnimals : an open access journal from MDPI · 2021
    Article
  14. Mucolytic bacteria: prevalence in various pathological diseases.World journal of microbiology & biotechnology · 2021
    Review
  15. Article
  16. Article
  17. Altered glycosylation in cancer: A promising target for biomarkers and therapeutics.Biochimica et biophysica acta. Reviews on cancer · 2021
    Review
  18. Chemotactic behavior ofAnimal reproduction · 2021
    Article
  19. Review
  20. TheToxins · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Abofu AlemkaDepartment of Biological Sciences, University of Alberta Edmonton, AB, Canada.
Nicolae Corcionivoschi
Billy Bourke
Children's Health Ireland at Crumlin · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mucus colonization is an essential early step toward establishing successful infection and disease by mucosal pathogens. There is an emerging literature implicating specific mucin sub-types and mucin modifications in protecting the host from Campylobacter jejuni infection. However, mucosal pathogens have evolved sophisticated mechanisms to breach the mucus layer and C. jejuni in particular appears to harbor specific adaptations to better colonize intestinal mucus. For example, components of mucus are chemotactic for C. jejuni and the rheological properties of mucus promote motility of the organism. Furthermore, recent studies demonstrate that mucins modulate the pathogenicity of C. jejuni in a species-specific manner and likely help determine whether these bacteria become pathogenic (as in humans), or adopt a commensal mode of existence (as in chickens and other animals). This review focuses on recent advances in understanding the complex interplay between C. jejuni and components of the mucus layer.

Indexed as

Host-Pathogen InteractionsAnimalsCampylobacter jejuniHumansIntestinal MucosaMucusCampylobacterchickensmotilitymucinsmucuspathogenicity

Identifiers

PMID22919607
PMCPMC3417559
OpenAlexW2115675625

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.