SynthesisThe British journal of radiology2012
Radiological staging in patients with hilar cholangiocarcinoma: a systematic review and meta-analysis.
Synthesis in The British journal of radiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
80 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- SEOM-GEMCAD-TTD clinical guidelines for biliary tract cancer (2025).Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025Guideline
- Diagnostic Performance of Radiolabelled FAPI Versus [International journal of molecular sciences · 2025Pooled it
- Radiological Imaging for Assessing the Respectability of Hilar Cholangiocarcinoma: A Systematic Review and Meta-Analysis.BioMed research international · 2015Pooled it
- Comparison of split bolus dual energy CT and standard multiphase CT in assessing vascular invasion in patients with biliary malignancies: a randomized study.Abdominal radiology (New York) · 2026Trial
- Intraoperative Paraaortic Lymph Node Sampling to Guide Surgical Decision-Making in Perihilar Cholangiocarcinoma.Annals of surgical oncology · 2026Article
- Real-world evidence in a large cohort comparing FAPI and FDG PET/CT for hepatopancreatobiliary cancer diagnosis.European journal of nuclear medicine and molecular imaging · 2026Article
- Current Status of Drug Treatment of Cholangiocarcinoma-Updated Progress and Critical Limitations.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Article
- Efficacy of three-dimensional fast spin echo T2-weighted magnetic resonance imaging (Cube) for evaluating the longitudinal spread of perihilar cholangiocarcinoma after endoscopic biliary stenting: a diagnostic study.International journal of surgery (London, England) · 2026Article
- Endoscopic Ultrasound for Nodal Staging in Patients with Resectable Cholangiocarcinoma.Journal of clinical medicine · 2025Article
- Progress in the application of fludeoxyglucose positron emission tomography computed tomography in biliary tract cancer.World journal of hepatology · 2025Review
- Standardized reporting of intrahepatic cholangiocarcinoma.Abdominal radiology (New York) · 2025Review
- Diagnostic cholangioscopy for surgical planning of extrahepatic cholangiocarcinoma.Scientific reports · 2025Article
- Preoperative Imaging Assessment and Staging of Perihilar Cholangiocarcinoma: Tips and Pitfalls.Journal of the Korean Society of Radiology · 2025Review
- Interobserver variability in lymph node evaluation with endoscopic ultrasonography in cholangiocarcinoma.Endoscopy international open · 2025Article
- The evolving landscape of biliary tract cancers: comparing French and US National Comprehensive Cancer Network guidelines.Hepatobiliary surgery and nutrition · 2024Article
- Practice guidelines for managing extrahepatic biliary tract cancers.Annals of hepato-biliary-pancreatic surgery · 2024Article
- Role of Intraoperative Frozen Section Assessment of Proximal Bile Duct Margins and the Impact of Additional Re-Resection in Perihilar Cholangiocarcinomas.Indian journal of surgical oncology · 2024Article
- Cholangiocarcinoma imaging: from diagnosis to response assessment.Abdominal radiology (New York) · 2024Review
- Radiographic features predictive of recurrence and survival after surgical resection of perihilar cholangiocarcinoma.Heliyon · 2024Article
20 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo obtain diagnostic performance values of CT, MRI, ultrasound and 18-fludeoxyglucose positron emission tomography (PET)/CT for staging of hilar cholangiocarcinoma.
methodsA comprehensive systematic search was performed for articles published up to March 2011 that fulfilled the inclusion criteria. Study quality was assessed with the quality assessment of diagnostic accuracy studies tool.
results16 articles (448 patients) were included that evaluated CT (n=11), MRI (n=3), ultrasound (n=3), or PET/CT (n=1). Overall, their quality was moderate. The accuracy estimates for evaluation of CT for ductal extent of the tumour was 86%. The sensitivity and specificity estimates of CT were 89% and 92% for evaluation of portal vein involvement, 83% and 93% for hepatic artery involvement, and 61% and 88% for lymph node involvement, respectively. Data were too limited for adequate comparisons of the different techniques.
conclusionDiagnostic accuracy studies of CT, MRI, ultrasound or PET/CT for staging of hilar cholangiocarcinoma are sparse and have moderate methodological quality. Data primarily concern CT, which has an acceptable accuracy for assessment of ductal extent, portal vein and hepatic artery involvement, but low sensitivity for nodal status.
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