Evidence map›Paper›PMID 22918550›Full record

ArticleJournal of materials science. Materials in medicine2012

Surface characterization and biocompatibility of titanium alloys implanted with nitrogen by Hardion+ technology.

D M Gordin, T Gloriant, V Chane-Pane, D Busardo, V Mitran, D Höche, C Vasilescu, S I Drob, A Cimpean

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Article in Journal of materials science. Materials in medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

D M GordinINSA Rennes, UMR CNRS 6226 Sciences Chimiques de Rennes/Chimie Métallurgie, 20 Avenue des Buttes de Coësmes, 35043, Rennes Cedex, France.
T Gloriant
V Chane-Pane
D Busardo
V Mitran
D Höche
C Vasilescu
S I Drob
A Cimpean

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, the new Hardion+ micro-implanter technology was used to modify surface properties of biomedical pure titanium (CP-Ti) and Ti-6Al-4V ELI alloy by implantation of nitrogen ions. This process is based on the use of an electron cyclotron resonance ion source to produce a multienergetic ion beam from multicharged ions. After implantation, surface analysis methods revealed the formation of titanium nitride (TiN) on the substrate surfaces. An increase in superficial hardness and a significant reduction of friction coefficient were observed for both materials when compared to non-implanted samples. Better corrosion resistance and a significant decrease in ion release rates were observed for N-implanted biomaterials due to the formation of the protective TiN layer on their surfaces. In vitro tests performed on human fetal osteoblasts indicated that the cytocompatibility of N-implanted CP-Ti and Ti-6Al-4V alloy was enhanced in comparison to that of the corresponding non treated samples. Consequently, Hardion+ implantation technique can provide titanium alloys with better qualities in terms of corrosion resistance, cell proliferation, adhesion and viability.

Indexed as

AlloysBiocompatible MaterialsCell AdhesionCell ProliferationCell SurvivalCorrosionExtracellular MatrixFibronectinsHumansIonsMass SpectrometryMaterials TestingNitrogenOsteoblastsProstheses and ImplantsSurface PropertiesAlloysBiocompatible MaterialsFibronectinsIonsNitrogenTitaniumtitanium nitride

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.