ArticlePediatric radiology2012
Effectiveness and safety of ultrasound-guided percutaneous liver biopsy in children.
Article in Pediatric radiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 48 citations in OpenAlex.
- Incidence of Complications from Percutaneous Biopsy in Chronic Liver Disease: A Systematic Review and Meta-Analysis.Digestive diseases and sciences · 2022Pooled it
- NASPGHAN Clinical Practice Guideline for the Diagnosis and Treatment of Nonalcoholic Fatty Liver Disease in Children: Recommendations from the Expert Committee on NAFLD (ECON) and the North American Society of Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN).Journal of pediatric gastroenterology and nutrition · 2017Guideline
- Prospective comparison of an 18-gauge versus 16-gauge needle for percutaneous liver core-needle biopsy in children.Abdominal radiology (New York) · 2024Trial
- Incidence and Predictors of Complications Following Percutaneous Liver Biopsy: A Large Italian Multicentre Study.Liver international : official journal of the International Association for the Study of the Liver · 2025Article
- Nontargeted Liver Biopsy in Children.Seminars in interventional radiology · 2025Review
- Paediatric liver biopsies: A single-centre experience in Erzincan Binali Yıldırım University.Ultrasound (Leeds, England) · 2024Article
- Pediatric liver cirrhosis interventional procedures: from biopsy to transjugular intrahepatic portosystemic shunt.Pediatric radiology · 2023Article
- Percutaneous ultrasound-guided cholecystocholangiography with microbubbles combined with liver biopsy for the assessment of suspected biliary atresia.Pediatric radiology · 2022Article
- Variation in Alanine Aminotransferase in Children with Non-Alcoholic Fatty Liver Disease.Children (Basel, Switzerland) · 2022Article
- The utility of post-biopsy ultrasonography in detecting complications after percutaneous liver biopsy in children.Pediatric radiology · 2020Article
- Diagnostic role of medical thoracoscopy in childhood pleural tuberculosis.Scientific reports · 2019Article
- Predictors of bleeding complications following percutaneous image-guided liver biopsy: a scoping review.Diagnostic and interventional radiology (Ankara, Turkey) · 2019Article
- Role of interventional radiology in managing pediatric liver tumors : Part 2: percutaneous interventions.Pediatric radiology · 2018Review
- Computed tomography-guided biopsies in children: accuracy, efficiency and dose usage.Italian journal of pediatrics · 2017Article
- "Safety and utility of percutaneous liver biopsy in hematopoietic stem cell transplant pediatric recipients: a retrospective study".BMC cancer · 2016Article
- Hepatic and Splenic Acoustic Radiation Force Impulse Shear Wave Velocity Elastography in Children with Liver Disease Associated with Cystic Fibrosis.BioMed research international · 2015Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPercutaneous liver biopsy (PLB) is an important procedure in the diagnosis and follow-up of paediatric liver disease. Its purpose is to obtain tissue for histopathological observation, in our case, with ultrasound (US) guidance.
objectiveTo evaluate the effectiveness and safety of US-guided PLB in children. MATERIAL AND
methodsA retrospective study over a period of 12 years, from January 1999 until December 2010, with a selection of US-guided PLB performed in children with focal liver lesions or diffuse hepatic disease and liver transplant (LT). A 16-gauge automatic needle was used and a maximum of three fragments of liver were collected. Contraindications were: bile duct dilatation (>3 mm) INR > 1.5 (reference range, 0.9 -- 1.2) and platelet count <50,000 (reference range, 150,000 -- 450,000). Analysis focused on complications and final diagnosis.
resultsA total of 513 biopsies were performed, 379 (73.9%) in children who had undergone orthotopic LT, 117 (22.8%) in children with liver disease of unknown cause and 17 (3.3%) in children with focal hepatic lesions. Histological diagnosis was obtained in 509 of 513 (99.3%) biopsies performed. Minor complications were registered in 38 patients (7.4%) and major complications occurred in 5 patients (1%). None needed a surgical intervention.
conclusionUS-guided PLB in children is a safe and efficient method to achieve a specific diagnosis in liver disease.
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