Evidence map›Paper›PMID 22917712›Full record

ArticleJournal of pain and symptom management2013

Lack of energy: an important and distinct component of HIV-related fatigue and daytime function.

Bradley E Aouizerat, Caryl L Gay, Anners Lerdal, Carmen J Portillo, Kathryn A Lee

Abstract read
In one paragraph

Article in Journal of pain and symptom management, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Fatigue in HIV-Infected People: A Three-Year Observational Study.Journal of pain and symptom management · 2015
    Observational
  12. Article
  13. Article
  14. Sleep, Fatigue, and Problems With Cognitive Function in Adults Living With HIV.The Journal of the Association of Nurses in AIDS Care : JANAC
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bradley E AouizeratDepartment of Physiological Nursing and Institute for Human Genetics, University of California at San Francisco, San Francisco, California 94143, USA. bradley.aouizerat@nursing.ucsf.edu
Caryl L Gay
Anners Lerdal
Carmen J Portillo
Kathryn A Lee

Funding

UCSF CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTEUL1RR024131 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSTON, S. CLAIBORNE · 2006 to 2011
$111.2M
Virology CoreP30AI027763 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI STEVEN Grant DEEKS · 1988 to 2026
$93.6M
CTSA: K12 COMPONENTKL2RR024130 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSTON, S. CLAIBORNE · 2006 to 2011
$19.3M
Biomarkers of Insomnia and Fatigue in HIV/AIDSR01MH074358 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LEE, KATHRYN · 2004 to 2007
$2.1M
NCRR NIH HHS 1 UL RR024131NCRR NIH HHS KL2 RR024130NCRR NIH HHS KL2RR024130NCRR NIH HHS UL1 RR024131NIAID NIH HHS P30 AI027763NIMH NIH HHS 5 R01 MH074358NIMH NIH HHS R01 MH074358
6 · The paper itself

Abstract

contextFatigue is a prevalent symptom among adults living with HIV. There is increasing evidence that fatigue and energy are related, yet distinct constructs. Although HIV-related fatigue has been well studied, little is known about perceived energy and how it relates to fatigue, individual characteristics, and other symptoms.

objectivesTo describe the experience of perceived energy in adults with HIV and evaluate its relationship to demographic and clinical characteristics as well as symptoms of fatigue, sleep disturbance, anxiety, depression, and daytime function.

methodsThe design was descriptive, comparative, and correlational. The sample of 318 adults with HIV completed a demographic questionnaire; the Memorial Symptom Assessment Scale; and measures of fatigue, sleep disturbance, anxiety, depressive symptoms, and daytime function. Medical records were reviewed for disease and treatment data. Participants who reported a lack of energy were compared with those who did not on demographic, clinical, and symptom variables. Regression models of perceived energy and its interference with daytime function also were evaluated.

resultsPerceived lack of energy was highly prevalent (65%) and more strongly related to interference with daytime function than more general measures of fatigue severity, even when controlling for other characteristics and symptoms. Like other aspects of fatigue, lack of energy was associated with sleep disturbance, anxiety, and depressive symptoms. Lack of energy was more strongly related to morning fatigue than to evening fatigue.

conclusionLack of energy interferes with daytime function and is not just the inverse of fatigue but a distinct perception that differs from fatigue.

Indexed as

Quality of LifeAdultAgedAged, 80 and overAnxietyComorbidityDepressionFatigueFemaleHIV InfectionsHumansLethargyLongitudinal StudiesMaleMiddle AgedPrevalence

Identifiers

PMID22917712
PMCPMC3547130

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.