ArticleClinical journal of the American Society of Nephrology : CJASN2012
The association of albumin/creatinine ratio with postoperative AKI in children undergoing cardiac surgery.
Article in Clinical journal of the American Society of Nephrology : CJASN, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Japanese clinical practice guideline for acute kidney injury 2016.Clinical and experimental nephrology · 2018Guideline
- Impact of low pneumoperitoneum on renal function and acute kidney injury biomarkers during robot-assisted radical prostatectomy (RARP): a randomised clinical trial.Journal of robotic surgery · 2024Trial
- A nomogram model for predicting acute kidney injury in critically ill patients with upper gastrointestinal bleeding: a study based on the MIMIC-IV database and external validation.BMC gastroenterology · 2026Article
- The predictive value of the serum creatinine-to-albumin ratio (sCAR) and lactate dehydrogenase-to-albumin ratio (LAR) in sepsis-related persistent severe acute kidney injury.European journal of medical research · 2025Article
- Clinical and subclinical acute kidney injury in children with mild-to-moderate COVID-19.Pediatric research · 2023Article
- The relationship between hyperchloremia and acute kidney injury in pediatric diabetic ketoacidosis and its impact on clinical outcomes.Pediatric nephrology (Berlin, Germany) · 2022Article
- Perioperative albuminuria and clinical model to predict acute kidney injury in paediatric cardiac surgery.Pediatric nephrology (Berlin, Germany) · 2022Observational
- Conceptual advances and evolving terminology in acute kidney disease.Nature reviews. Nephrology · 2021Review
- Acute Kidney Injury and Risk of CKD and Hypertension after Pediatric Cardiac Surgery.Clinical journal of the American Society of Nephrology : CJASN · 2020Observational
- Glyphosate exposures and kidney injury biomarkers in infants and young children.Environmental pollution (Barking, Essex : 1987) · 2020Article
- Early prediction of acute kidney injury in neonates with cardiac surgery.World journal of pediatric surgery · 2020Review
- Biomarkers of AKI Progression after Pediatric Cardiac Surgery.Journal of the American Society of Nephrology : JASN · 2018Article
- Pre-admission proteinuria impacts risk of non-recovery after dialysis-requiring acute kidney injury.Kidney international · 2018Article
- The Japanese Clinical Practice Guideline for acute kidney injury 2016.Journal of intensive care · 2018Article
- Interleukin-8 and Tumor Necrosis Factor Predict Acute Kidney Injury After Pediatric Cardiac Surgery.The Annals of thoracic surgery · 2017Article
- Urine biomarkers of acute kidney injury in noncritically ill, hospitalized children treated with chemotherapy.Pediatric blood & cancer · 2017Observational
- Nephrotoxicity-induced proteinuria increases biomarker diagnostic thresholds in acute kidney injury.BMC nephrology · 2017Observational
- Evaluation of clinically available renal biomarkers in critically ill adults: a prospective multicenter observational study.Critical care (London, England) · 2017Observational
- AKI after pediatric cardiac surgery for congenital heart diseases-recent developments in diagnostic criteria and early diagnosis by biomarkers.Journal of intensive care · 2017Review
- Longitudinal patterns of urine biomarkers in infants across gestational ages.Pediatric nephrology (Berlin, Germany) · 2016Article
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10 authors.
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Abstract
BACKGROUND AND
objectivesThis study determined if preoperative and postoperative urine albumin/creatinine ratios (ACRs) predict postoperative AKI in children undergoing cardiac surgery (CS). DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: This was a three-center, prospective study (2007-2009) of 294 children undergoing CS (n=145 aged <2 years). Urine ACR was measured preoperatively and 0-6 hours after intensive care unit arrival. AKI outcomes were based on the Acute Kidney Injury Network serum creatinine (SCr) criteria (stage 1 AKI, ≥50% or 0.3 mg/dl SCr rise from baseline; and stage 2 or worse AKI, ≥SCr doubling or dialysis). AKI was predicted using preoperative and postoperative ACRs and postoperative ACR performance was compared with other AKI biomarkers.
resultsPreoperative ACR did not predict AKI in younger or older children. In children aged <2 years, first postoperative ACR ≥908 mg/g (103 mg/mmol) predicted stage 2 AKI development (adjusted relative risk, 3.4; 95% confidence interval, 1.2-9.4). In children aged ≥2 years, postoperative ACR ≥169 mg/g (19.1 mg/mmol) predicted stage 1 AKI (adjusted relative risk, 2.1; 95% confidence interval, 1.1-4.1). In children aged ≥2 years, first postoperative ACR improved AKI prediction from other biomarker and clinical prediction models, estimated by net reclassification improvement (P≤0.03), but only when serum cystatin C was also included in the model.
conclusionsPostoperative ACR is a readily available early diagnostic test for AKI after pediatric CS that performs similarly to other AKI biomarkers; however, its use is enhanced in children aged ≥2 years and in combination with serum cystatin C.
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