Evidence map›Paper›PMID 22917025›Full record

ReviewBMC medicine2012

Physiopathology of intratendinous calcific deposition.

Francesco Oliva, Alessio Giai Via, Nicola Maffulli

Registry-linked trialAbstract readReview
In one paragraph

Review in BMC medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02776345 (Study to Evaluate Ultrasound Guided Interventions of Calcific Tendonitis of Rotator Cuff- International CollabratioN), which is not on this map. Cited by 102 papers.

0numbers the graph read from it
0cells of the map it votes in
102citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02776345 naunknown statusnot on this mapstarted 2021, after this paper: background citation

Study to Evaluate Ultrasound Guided Interventions of Calcific Tendonitis of Rotator Cuff- International CollabratioN (SUCTION)

TypeinterventionalSponsorHamilton Health Sciences CorporationRan2021 to 2022Enrolled160ConditionsRotator Cuff Calcific TendonitisArmsUltrasound guided Needle Fragmentation, US guided needle fragmentation & Lavage, Ultrasound guided subacromial injection
3 · Its place in the literature

Who cites it

102 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Power Doppler Ultrasound After Ultrasound-Guided Lavage of Rotator Cuff Calcific Tendinopathy: Association With Clinical Outcomes.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2026
    Article
  4. Article
  5. Article
  6. Pathogenesis of Shoulder Calcific Tendinopathy.International journal of molecular sciences · 2026
    Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Observational
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Observational

42 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Francesco OlivaDepartment of Orthopaedics and Traumatology, University of Rome 'Tor Vergata' School of Medicine, Viale Oxford 81, Rome, Italy.
Alessio Giai Via
Nicola Maffulli

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In calcific tendinopathy (CT), calcium deposits in the substance of the tendon, with chronic activity-related pain, tenderness, localized edema and various degrees of decreased range of motion. CT is particularly common in the rotator cuff, and supraspinatus, Achilles and patellar tendons. The presence of calcific deposits may worsen the clinical manifestations of tendinopathy with an increase in rupture rate, slower recovery times and a higher frequency of post-operative complications. The aetiopathogenesis of CT is still controversial, but seems to be the result of an active cell-mediated process and a localized attempt of the tendon to compensate the original decreased stiffness. Tendon healing includes many sequential processes, and disturbances at different stages of healing may lead to different combinations of histopathological changes, diverting the normal healing processes to an abnormal pathway. In this review, we discuss the theories of pathogenesis behind CT. Better understanding of the pathogenesis is essential for development of effective treatment modalities and for improvement of clinical outcomes.

Indexed as

CalcinosisHumansTendinopathy

Identifiers

PMID22917025
PMCPMC3482552

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.