ArticlePloS one2012
Tertiary endosymbiosis in two dinotoms has generated little change in the mitochondrial genomes of their dinoflagellate hosts and diatom endosymbionts.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 65 citations in OpenAlex.
- An acetyltransferase family required for biosynthesis of diverse marine carotenoids.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Spatial fragmentation in the distribution of diatom endosymbionts from the taxonomically clarified dinophyte Kryptoperidinium triquetrum (= Kryptoperidinium foliaceum, Peridiniales).Scientific reports · 2023Article
- Organellar Evolution: A Path from Benefit to Dependence.Microorganisms · 2022Review
- Diatom Biodiversity and Speciation Revealed by Comparative Analysis of Mitochondrial Genomes.Frontiers in plant science · 2022Article
- Article
- Definition of a High-Resolution Molecular Marker for Tracking the Genetic Diversity of the Harmful Algal SpeciesFrontiers in microbiology · 2021Article
- Dinoflagellates with relic endosymbiont nuclei as models for elucidating organellogenesis.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Recent advances in understanding mitochondrial genome diversity.F1000Research · 2020Review
- A single-cell genome perspective on studying intracellular associations in unicellular eukaryotes.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019Article
- A kleptoplastidic dinoflagellate and the tipping point between transient and fully integrated plastid endosymbiosis.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- In the beginning was the word: How terminology drives our understanding of endosymbiotic organelles.Microbial cell (Graz, Austria) · 2019Article
- Recurrent Loss, Horizontal Transfer, and the Obscure Origins of Mitochondrial Introns in Diatoms (Bacillariophyta).Genome biology and evolution · 2018Article
- Peculiarities within peculiarities - dinoflagellates and their mitochondrial genomes.Mitochondrial DNA. Part B, Resources · 2017Article
- Evolutionary distinctiveness of fatty acid and polyketide synthesis in eukaryotes.The ISME journal · 2016Article
- A Comparative Analysis of Mitochondrial Genomes in Eustigmatophyte Algae.Genome biology and evolution · 2016Article
- Integration of plastids with their hosts: Lessons learned from dinoflagellates.Proceedings of the National Academy of Sciences of the United States of America · 2015Review
- The Large Mitochondrial Genome of Symbiodinium minutum Reveals Conserved Noncoding Sequences between Dinoflagellates and Apicomplexans.Genome biology and evolution · 2015Article
- Evidence for the retention of two evolutionary distinct plastids in dinoflagellates with diatom endosymbionts.Genome biology and evolution · 2014Article
- Horizontal gene transfer and redundancy of tryptophan biosynthetic enzymes in dinotoms.Genome biology and evolution · 2014Article
- Endosymbiotic gene transfer in tertiary plastid-containing dinoflagellates.Eukaryotic cell · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMitochondria or mitochondrion-derived organelles are found in all eukaryotes with the exception of secondary or tertiary plastid endosymbionts. In these highly reduced systems, the mitochondrion has been lost in all cases except the diatom endosymbionts found in a small group of dinoflagellates, called 'dinotoms', the only cells with two evolutionarily distinct mitochondria. To investigate the persistence of this redundancy and its consequences on the content and structure of the endosymbiont and host mitochondrial genomes, we report the sequences of these genomes from two dinotoms. METHODOLOGY/PRINCIPAL
findingsThe endosymbiont mitochondrial genomes of Durinskia baltica and Kryptoperidinium foliaceum exhibit nearly identical gene content with other diatoms, and highly conserved gene order (nearly identical to that of the raphid pennate diatom Fragilariopsis cylindrus). These two genomes are differentiated from other diatoms' by the fission of nad11 and by an insertion within nad2, in-frame and unspliced from the mRNA. Durinskia baltica is further distinguished from K. foliaceum by two gene fusions and its lack of introns. The host mitochondrial genome in D. baltica encodes cox1 and cob plus several fragments of LSU rRNA gene in a hugely expanded genome that includes numerous pseudogenes, and a trans-spliced cox3 gene, like in other dinoflagellates. Over 100 distinct contigs were identified through 454 sequencing, but intact full-length genes for cox1, cob and the 5' exon of cox3 were present as a single contig each, suggesting most of the genome is pseudogenes. The host mitochondrial genome of K. foliaceum was difficult to identify, but fragments of all the three protein-coding genes, corresponding transcripts, and transcripts of several LSU rRNA fragments were all recovered. CONCLUSIONS/SIGNIFICANCE: Overall, the endosymbiont and host mitochondrial genomes in the two dinotoms have changed surprisingly little from those of free-living diatoms and dinoflagellates, irrespective of their long coexistence side by side in dinotoms.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.