Evidence map›Paper›PMID 22916137›Full record

ArticlePloS one2012

Predictors and prevalence of latent tuberculosis infection in patients receiving long-term hemodialysis and peritoneal dialysis.

Chin-Chung Shu, Vin-Cent Wu, Feng-Jung Yang, Sung-Ching Pan, Tai-Shuan Lai, Jann-Yuan Wang, Jann-Tay Wang, Li-Na Lee

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 7 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 7 syntheses or guidelines pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Risk of Tuberculosis Disease in People With Chronic Kidney Disease Without Kidney Failure: A Systematic Review and Meta-analysis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Diabetes Mellitus and Latent Tuberculosis Infection: A Systematic Review and Metaanalysis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2017
    Pooled it
  8. Article
  9. Article
  10. Article
  11. Risk factors of latent tuberculosis among chronic kidney disease with routine haemodialysis patients.Journal of clinical tuberculosis and other mycobacterial diseases · 2022
    Article
  12. Article
  13. Observational
  14. Article
  15. Article
  16. Failure to complete treatment for latent tuberculosis infection in Portugal, 2013-2017: geographic-, sociodemographic-, and medical-associated factors.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2020
    Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Chin-Chung ShuDepartment of Traumatology, National Taiwan University Hospital, Taipei City, Taiwan.
Vin-Cent Wu
Feng-Jung Yang
Sung-Ching Pan
Tai-Shuan Lai
Jann-Yuan Wang
Jann-Tay Wang
Li-Na Lee
National Taiwan University · TWNational Taiwan University Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTuberculosis is a common infectious disease in long-term dialysis patients. The prevalence of latent tuberculosis infection (LTBI) in this population is unclear, particularly in those receiving peritoneal dialysis (PD). This study investigated the prevalence of LTBI in patients receiving either hemodialysis (HD) or PD to determine predictors of LTBI and indeterminate results of interferon-gamma release assay.

methodsPatients receiving long-term (≥ 3 months) HD or PD from March 2011 to February 2012 in two medical centers were prospectively enrolled. QuantiFERON-Gold in tube (QFT) test was used to determine the status of LTBI after excluding active tuberculosis. The LTBI prevalence was determined in patients receiving different dialysis modes to obtain predictors of LTBI and QFT-indeterminate results.

resultsOf 427 patients enrolled (124 PD and 303 HD), 91 (21.3%) were QFT-positive, 316 (74.0%) QFT-negative, and 20 (4.7%) QFT-indeterminate. The prevalence of LTBI was similar in the PD and HD groups. Independent predictors of LTBI were old age (OR: 1.034 [1.013-1.056] per year increment), TB history (OR: 6.467 [1.985-21.066]), and current smoker (OR: 2.675 [1.061-6.747]). Factors associated with indeterminate QFT results were HD (OR: 10.535 [1.336-83.093]), dialysis duration (OR: 1.113 [1.015-1.221] per year increment), anemia (OR: 8.760 [1.014-75.651]), and serum albumin level (OR: 0.244 [0.086-0.693] per 1 g/dL increment).

conclusionMore than one-fifth of dialysis patients have LTBI. The LTBI prevalence is similar in PD and HD patients but is higher in the elderly, current smokers, and those with prior TB history. Such patients require closer follow-up. Repeated or alternative test may be required for malnutrition patients who received long length of HD.

Indexed as

Peritoneal DialysisRenal DialysisAgedCross-Sectional StudiesFemaleHumansKidney DiseasesMaleMiddle AgedPrevalenceTaiwanTuberculosis

Identifiers

PMID22916137
PMCPMC3423405
OpenAlexW2013541410

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.