Evidence map›Paper›PMID 22916039›Full record

ArticlePLoS genetics2012

It's all in the timing: too much E2F is a bad thing.

Brandon N Nicolay, Nicholas J Dyson

Abstract read
In one paragraph

Article in PLoS genetics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Brandon N NicolayMassachusetts General Hospital Cancer Research Center, Charlestown, Massachusetts, United States of America.
Nicholas J Dyson

Funding

MUTAGENESIS OF THE PRB POCKET DOMAINR01CA064402 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI DYSON, NICHOLAS J · 1994 to 2015
$4.1M
The Origins of Chromosomal Instability in Human Tumor CellsR01CA155202 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI DYSON, NICHOLAS J · 2011 to 2015
$1.8M
Understanding the role of SKP2 in small cell lung cancer progressionF32CA165856 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI NICOLAY, BRANDON · 2012 to 2014
$149k
NCI NIH HHS CA155202NCI NIH HHS CA64402NCI NIH HHS F32 CA165856NCI NIH HHS R01 CA064402NCI NIH HHS R01 CA155202
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene Expression RegulationAnimalsApoptosisCell ProliferationDNADrosophila melanogasterDrosophila ProteinsE2F1 Transcription FactorHumansNeuropeptidesRetinoblastoma ProteinS PhaseTime FactorsTranscription FactorsDNADrosophila ProteinsE2F1 Transcription FactorHID protein, DrosophilaNeuropeptidesRbf protein, DrosophilaRetinoblastoma ProteinTranscription Factors

Identifiers

PMID22916039
PMCPMC3420940

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.