ArticleJournal of clinical microbiology2012
Chlamydia trachomatis strains show specific clustering for men who have sex with men compared to heterosexual populations in Sweden, the Netherlands, and the United States.
Article in Journal of clinical microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 37 citations in OpenAlex.
- Lymphogranuloma Venereum Detection in Chlamydia trachomatis Positive Self-Collected Mail-in Male Rectal Samples in Maryland, United States.Sexually transmitted diseases · 2025Article
- Genetic Characterization of Non-International journal of molecular sciences · 2023Article
- Emergence of NovelMicroorganisms · 2022Article
- Distribution ofFrontiers in public health · 2022Article
- Use of real-time PCR as an alternative to conventional genotyping methods for the laboratory detection of lymphogranuloma venereum (LGV).Diagnostic microbiology and infectious disease · 2021Article
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- Higher organism load associated with failure of azithromycin to treat rectal chlamydia.Epidemiology and infection · 2016Article
- Does typing of Chlamydia trachomatis using housekeeping multilocus sequence typing reveal different sexual networks among heterosexuals and men who have sex with men?BMC infectious diseases · 2016Article
- Global Multilocus Sequence Type Analysis of Chlamydia trachomatis Strains from 16 Countries.Journal of clinical microbiology · 2015Article
- In silico scrutiny of genes revealing phylogenetic congruence with clinical prevalence or tropism properties of Chlamydia trachomatis strains.G3 (Bethesda, Md.) · 2014Article
- Novel Chlamydia trachomatis strains in heterosexual sex partners, Indianapolis, Indiana, USA.Emerging infectious diseases · 2014Article
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- No indication for tissue tropism in urogenital and anorectal Chlamydia trachomatis infections using high-resolution multilocus sequence typing.BMC infectious diseases · 2014Article
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Corrections and comments
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Authors and funding
9 authors at 5 institutions in 3 countries.
Funding
Abstract
High-resolution genotyping of Chlamydia trachomatis improves the characterization of strains infecting different patient groups and sexual networks. In this study, multilocus sequence typing (MLST) and ompA sequence determination were used for an analysis of C. trachomatis strains from 203 men who have sex with men (MSM) from Sweden, the Netherlands, and the United States. The results obtained were compared with data from 153 heterosexual women from Sweden and the Netherlands. The overlap in MLST/ompA profiles between MSM from Sweden and the Netherlands was 68%, while the overlap between heterosexual populations from these countries was only 18%. The distribution of genotypes in MSM from the United States was less similar to that in MSM from the European countries, with 45% and 46% overlaps for MSM in Sweden and the Netherlands, respectively. Minimum-spanning-tree analysis of MLST/ompA sequence types identified two large clusters that contained almost exclusively samples from MSM and comprised 74% of all MSM samples. Three other clusters were predominated by samples from women but also contained MSM specimens. Of 19 detected variants of the MLST target CT144, three variants were highly associated with MSM. Our study supports the hypotheses of both tissue tropism as well as epidemiological network structures as explanations for the linkage between specific genetic variants and sexual orientation.
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Registered trials
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