ArticleUrological research2012
Medicinal plants extracts affect virulence factors expression and biofilm formation by the uropathogenic Escherichia coli.
Article in Urological research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 115 citations in OpenAlex.
- Antimicrobial potential of selected medicinal plants against drug-resistant pathogens: a systematic review.Frontiers in pharmacology · 2026Pooled it
- Phytochemistry, Antimicrobial, Analgesic, Antibiofilm, Diuretic Activities, and Acute Toxicity of Bark Extracts From Three Plants (Khaya senegalensis, Ocimum americanum, and Cassytha filiformis) Collected in Benin.TheScientificWorldJournal · 2026Article
- Current Insights into Antibiotic Resistance in UropathogenicAntibiotics (Basel, Switzerland) · 2025Review
- Antimicrobial activity of cranberry juice (Open veterinary journal · 2025Review
- A synergistic herbal formulation targetingFrontiers in microbiology · 2025Article
- Natural Products in the Treatment of Lower Urinary Tract Dysfunction and Infection.Handbook of experimental pharmacology · 2025Review
- Design and Characterization of Novel Polymeric Hydrogels with Protein Carriers for Biomedical Use.International journal of molecular sciences · 2024Article
- Phenolic Content and Anti-Inflammatory Activity of Cultivated and Wild-TypeAntioxidants (Basel, Switzerland) · 2024Article
- Distribution of chaperone-usher fimbriae and curli fimbriae among uropathogenic Escherichia coli.BMC microbiology · 2024Article
- Article
- Genomic characterization of a multidrug-resistant uropathogenicAIMS microbiology · 2024Article
- Natural compounds in the fight againstFrontiers in pharmacology · 2024Review
- ExposingInternational journal of molecular sciences · 2023Article
- Inhibitory potential of natural plant extracts againstOpen veterinary journal · 2023Article
- Urinary Tract Infections Caused by UropathogenicInternational journal of molecular sciences · 2023Review
- An assessment of the evidence for antibacterial activity of stinging nettle (Access microbiology · 2022Article
- Nanoemulsions ofPharmaceutics · 2021Article
- Review
- Peptide Extracts from Seven Medicinal Plants Discovered to Inhibit OomycetePlants (Basel, Switzerland) · 2020Article
- Natural therapeutics for urinary tract infections-a review.Future journal of pharmaceutical sciences · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Medicinal plants are an important source for the therapeutic remedies of various diseases including urinary tract infections. This prompted us to perform research in this area. We decided to focus on medicinal plants species used in urinary tract infections prevention. The aim of our study was to determine the influence of Betula pendula, Equisetum arvense, Herniaria glabra, Galium odoratum, Urtica dioica, and Vaccinium vitis-idaea extracts on bacterial survival and virulence factors involved in tissue colonization and biofilm formation of the uropathogenic Escherichia coli rods. Qualitative and quantitative analysis of plant extracts were performed. Antimicrobial assay relied on the estimation of the colony forming unit number. Hydrophobicity of cells was established by salt aggregation test. Using motility agar, the ability of bacteria to move was examined. The erythrocyte hemagglutination test was used for fimbriae P screening. Curli expression was determined using YESCA agar supplemented with congo red. Quantification of biofilm formation was carried out using a microtiter plate assay and a spectrophotometric method. The results of the study indicate significant differences between investigated extracts in their antimicrobial activities. The extracts of H. glabra and V. vitis-idaea showed the highest growth-inhibitory effects (p < 0.05). Surface hydrophobicity of autoaggregating E. coli strain changed after exposure to all plant extracts, except V. vitis-idaea (p > 0.05). The B. pendula and U. dioica extracts significantly reduced the motility of the E. coli rods (p < 0.05). All the extracts exhibited the anti-biofilm activity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.