ArticleZeitschrift fur Gerontologie und Geriatrie2012
Polypharmacy in the elderly from the clinical toxicologist perspective.
Article in Zeitschrift fur Gerontologie und Geriatrie, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- Optimizing polypharmacy among elderly hospital patients with chronic diseases--study protocol of the cluster randomized controlled POLITE-RCT trial.Implementation science : IS · 2014Trial
- Article
- Number of medications and adverse drug events by unintentional poisoning among older adults in consideration of inappropriate drug use: a Swedish population-based matched case-control study.European journal of clinical pharmacology · 2017Article
- Predictors of Inadequate Bowel Preparation and Salvage Options on Colonoscopy.Clinical endoscopy · 2016Review
- The next therapeutic challenge in HIV: polypharmacy.Drugs & aging · 2013Review
- Factors influencing quality of bowel preparation for colonoscopy.World journal of gastrointestinal endoscopy · 2013Article
- Predictors and colonoscopy outcomes of inadequate bowel cleansing: a 10-year experience in 28,725 patients.Annals of gastroenterologyArticle
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPolypharmacy is closely associated with multimorbidity in the elderly and can lead to problems and drug interactions.
aimThis study assessed polypharmacy in the elderly, tracking inquiries to the Poison Information Centre Nuremberg (PICN) and patients needing toxicological intensive care therapy.
methodsFrom 2006-2009, all PICN inquiries involving individuals > 70 years were tracked, as were cases at the Toxicological Intensive Care Unit (T-ICU) regarding adverse drug reactions (ADRs) and drug poisoning.
resultsOf 11,683 PICN calls about pharmaceuticals, 175 (1.5%) were from people > 70 years; 156 (4.8%) of 3,272 T-ICU patients were > 70 years. Calls about psychopharmaceuticals (46.9%) and analgesics (25.7%) were most frequent. Among the T-ICU patients, psychopharmaceuticals like sedatives and hypnotics were frequently involved (20.5%), as were tricyclic antidepressants (17.9%) and analgesics (29.5%). Ethanol was co-ingested by 18.3%.
conclusionPopulation-specific poison prevention strategies are needed to reduce toxic exposures. Such strategies could include pharmacist intervention, improved prescriber communication and education regarding the geriatric population, and computerized drug databases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.