ArticleJournal of fluorescence2013
Feasibility study on quantitative measurements of singlet oxygen generation using singlet oxygen sensor green.
Article in Journal of fluorescence, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed, 149 citations in OpenAlex.
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- Sonodynamic Therapy for HER2+ Breast Cancer with Iodinated Heptamethine Cyanine-Trastuzumab Conjugate.International journal of molecular sciences · 2024Article
- Singlet oxygen detection in vivo is hindered by nonspecific SOSG staining.Scientific reports · 2024Article
- Core-Shell Interface Engineering Strategies for Modulating Energy Transfer in Rare Earth-Doped Nanoparticles.Nanomaterials (Basel, Switzerland) · 2024Article
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- Antibacterial and Antibiofouling Activities of Carbon Polymerized Dots/Polyurethane and CJournal of functional biomaterials · 2024Article
- Red Light-Triggered Anti-Angiogenic and Photodynamic Combination Therapy of Age-Related Macular Degeneration.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Recent advances in biosensors for real time monitoring of pH, temperature, and oxygen in chronic wounds.Materials today. Bio · 2023Review
- Screening of antioxidant capacity of Nepali medicinal plants with a novel singlet oxygen scavenging assay.Food science and biotechnology · 2023Article
- Effect of Solubilizing Group on the Antibacterial Activity of Heptamethine Cyanine Photosensitizers.Pharmaceutics · 2023Article
- Quantifying the Photochemical Damage Potential of Contrast-Enhanced Fluorescence Imaging Products: Singlet Oxygen Production.Photochemistry and photobiology · 2022Article
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- Hyaluronic acid carrier-based photodynamic therapy for head and neck squamous cell carcinoma.Photodiagnosis and photodynamic therapy · 2022Article
- Screening of Chitosan Derivatives-Carbon Dots Based on Antibacterial Activity and Application in Anti-International journal of nanomedicine · 2022Article
- Aggregation-induced emission luminogens for highly effective microwave dynamic therapy.Bioactive materials · 2022Article
- Two-photon activated precision molecular photosensitizer targeting mitochondria.Communications chemistry · 2021Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of this study is to investigate the feasibility for quantitative measurement of singlet oxygen ((1)O(2)) generation by using a newly developed (1)O(2)-specific fluorescence probe Singlet Oxygen Sensor Green reagent (SOSG). (1)O(2) generation from photoirradiation of a model photosensitizer Rose Bengal (RB), in initially air-statured phosphate buffered saline (PBS) was indirectly monitored with SOSG. In the presence of (1)O(2), SOSG can react with (1)O(2) to produce SOSG endoperoxides (SOSG-EP) that emit strong green fluorescence with the maximum at 531 nm. The green fluorescence of SOSG-EP is mainly dependent on the initial concentrations of RB and SOSG, and the photoirradiation time for (1)O(2) generation. Furthermore, kinetic analysis of the RB-sensitized photooxidation of SOSG is performed that, for the first time, allows quantitative measurement of (1)O(2) generation directly from the determination of reaction rate. In addition, the obtained (1)O(2) quantum yield of porphyrin-based photosensitizer hematoporphyrin monomethyl ether (HMME) in PBS by using SOSG is in good agreement with the value that independently determined by using direct measurement of (1)O(2) luminescence. The results of this study clearly demonstrate that the quantitative measurement of (1)O(2) generation using SOSG can be achieved by determining the reaction rate with an appropriate measurement protocol.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.