Evidence map›Paper›PMID 22913533›Full record

ReviewTraffic (Copenhagen, Denmark)2013

mRNA localization: an orchestration of assembly, traffic and synthesis.

Lei Xing, Gary J Bassell

Open access · bronzeAbstract readReview
In one paragraph

Review in Traffic (Copenhagen, Denmark), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 61 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Downstream Effects of Mutations inInternational journal of molecular sciences · 2022
    Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Sonic Hedgehog Guides Axons via Zipcode Binding Protein 1-Mediated Local Translation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Lei XingDepartment of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA.
Gary J Bassell
Emory University · US

Funding

Imaging FMRP regulation and functionR01MH085617 · NIMH · EMORY UNIVERSITY · PI BASSELL, GARY J · 2009 to 2013
$1.9M
Spinal Muscular Atrophy: SMNs role in MRNA localization and local translationR01HD055835 · NICHD · EMORY UNIVERSITY · PI BASSELL, GARY J · 2007 to 2011
$1.8M
Imaging FMRP Regulation and FunctionR01NS051127 · NINDS · EMORY UNIVERSITY · PI BASSELL, GARY J · 2005 to 2008
$1.3M
NICHD NIH HHS R01 HD055835NIMH NIH HHS R01 MH085617NINDS NIH HHS R01 NS051127
6 · The paper itself

Abstract

Asymmetrical mRNA localization and subsequent local translation provide efficient mechanisms for protein sorting in polarized cells. Defects in mRNA localization have been linked to developmental abnormalities and neurological diseases. Thus, it is critical to understand the machineries mediating and mechanisms underlying the asymmetrical distribution of mRNA and its regulation. The goal of this review is to summarize recent advances in the understanding of mRNA transport and localization, including the assembly and sorting of transport messenger ribonucleic protein (mRNP) granules, molecular mechanisms of active mRNP transport, cytoskeletal interactions and regulation of these events by extracellular signals.

Indexed as

AnimalsHumansMolecular Motor ProteinsRibonucleoproteinsRNA, MessengerRNA TransportSignal TransductionMolecular Motor ProteinsRibonucleoproteinsRNA, Messenger

Identifiers

PMID22913533
PMCPMC3548013
OpenAlexW1537032494

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.