Trial reportBMC women's health2012
Comparing the analgesic effect of heat patch containing iron chip and ibuprofen for primary dysmenorrhea: a randomized controlled trial.
Trial report in BMC women's health, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 4 syntheses or guidelines pooled it, 61 citations in OpenAlex.
- Heat therapy for primary dysmenorrhea: a systematic review and meta-analysis.Frontiers in medicine · 2025Pooled it
- An update and systematic review on the treatment of primary dysmenorrhea.JBRA assisted reproduction · 2019Pooled it
- The effectiveness of self-care and lifestyle interventions in primary dysmenorrhea: a systematic review and meta-analysis.BMC complementary and alternative medicine · 2019Pooled it
- Heat therapy for primary dysmenorrhea: A systematic review and meta-analysis of its effects on pain relief and quality of life.Scientific reports · 2018Pooled it
- Effect of an Acupuncture Technique of Penetrating throughPain research & management · 2019Trial
- Moxibustion for pain relief in patients with primary dysmenorrhea: A randomized controlled trial.PloS one · 2017Trial
- Effectiveness of medical taping concept in primary dysmenorrhoea: a two-armed randomized trial.Scientific reports · 2015Trial
- Safety of individualized herbal medicine for dysmenorrhea: pharmacovigilance from South Korea's national pilot.Frontiers in pharmacology · 2026Article
- Peppermint oil in menstrual disorders and menopausal symptoms: a research progress review.Frontiers in endocrinology · 2026Review
- Perception of university students about the use of painkillers, other remedies and lifestyle modifications for primary dysmenorrhea; a cross-sectional study at KEMU.BMC women's health · 2025Article
- Expert opinion on heat therapy for teenagers' musculoskeletal pain management.Annals of translational medicine · 2024Review
- Metabonomic Study of the Effect of Dingkundan Intervention Comparing with Oral Contraceptives on Primary Dysmenorrhea Using the UPLC-MS Technique.BioMed research international · 2022Article
- A Role for Superficial Heat Therapy in the Management of Non-Specific, Mild-to-Moderate Low Back Pain in Current Clinical Practice: A Narrative Review.Life (Basel, Switzerland) · 2021Review
- Integrating Lifestyle Focused Approaches into the Management of Primary Dysmenorrhea: Impact on Quality of Life.International journal of women's health · 2021Review
- Article
- Influence of the Intensity, Components, and Spreading of the Deqi Sensation on the Analgesic Effect of SP6 Needling in Primary Dysmenorrhea Patients: A Secondary Analysis of a Randomised Controlled Trial.Evidence-based complementary and alternative medicine : eCAM · 2019Article
- Weather and Health Symptoms.International journal of environmental research and public health · 2018Article
- Management of Usr-i-Tamth (Menstrual Pain) in Unani (Greco-Islamic) Medicine.Journal of evidence-based complementary & alternative medicine · 2017Review
- The Effect ofIranian journal of pharmaceutical research : IJPR · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrimary dysmenorrhea is a common and sometimes disabling condition. In recent years, some studies aimed to improve the treatment of dysmenorrhea, and therefore, introduced several therapeutic measures. This study was designed to compare the analgesic effect of iron chip containing heat wrap with ibuprofen for the treatment of primary dysmenorrhea.
methodsIn this randomized (IRCT201107187038N2) controlled trial, 147 students (18-30 years old) with the diagnosis of primary dysmenorrhea were enrolled considering the CONSORT guideline. Screening for primary dysmenorrhea was done by a two-question screening tool. The participants were randomly assigned into one of the intervention groups (heat Patch and ibuprofen). Data regarding the severity and emotional impact of the pain were recorded by a shortened version of McGill Pain Questionnaire (SF-MPQ). Student's t test was used for statistical analysis.
resultsThe maximum and minimum pain severities were observed at 2 and 24 hours in both groups. The severity of sensual pain at 8, 12, and 24 hours was non-significantly less in the heat Patch group. There was also no significant difference between the groups regarding the emotional impact of pain at the first 2, 4, 8, 12 and 12 hours of menstruation.
conclusionsHeat patch containing Iron chip has comparable analgesic effects to ibuprofen and can possibly be used for primary dysmenorrhea.
trial registrationIRCT201107187038N2.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.