ArticleCroatian medical journal2012
New insight into the role of NT-proBNP in alcoholic liver cirrhosis as a noninvasive marker of esophageal varices.
Article in Croatian medical journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 8 citations in OpenAlex.
- Markers of cardiac injury in patients with liver cirrhosis.Croatian medical journal · 2023Review
- A Combination of N-Terminal proB-Type Natriuretic Peptide and Myoglobin Can Predict Severe Complications After Major Non-Cardiac Surgery in Elderly Patients: A Prospective Observational Cohort Study.Frontiers in medicine · 2021Article
- Immature platelet fraction and thrombopoietin in patients with liver cirrhosis: A cohort study.PloS one · 2018Article
- Hazardous alcohol consumption is associated with increased levels of B-type natriuretic peptide: evidence from two population-based studies.European journal of epidemiology · 2013Article
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo investigate the association between plasma concentrations of N-terminal pro-B-type natriuretic peptide (NT-proBNP) and formation of esophageal varices.
methodsThirty-five patients with alcoholic cirrhosis were divided into three groups according to the Child-Pugh classification: grade A (n=11, 32%), B (n=12, 34%), and C (n=12, 34%). System hemodynamic parameters were measured using sphygmomanometry, electrocardiography, and echocardiography. NT-proBNP was analyzed by using an electrochemiluminiscence sandwich immunoassay.
resultsThe presence of esophageal varices was associated with a higher serum NT-proBNP level, with a cut-off value of <101 pg/mL (sensitivity, 87.60% and specificity, 72.73%; P<0.001).
conclusionsNT-proBNP was found to be a marker of the presence of esophageal varices, but not a marker of progression of liver cirrhosis. In cirrhotic patients, NT-proBNP value <101 pg/mL was shown to be a valuable noninvasive parameter in predicting the presence of varices.
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