Evidence map›Paper›PMID 22911514›Full record

ArticleBiochemical genetics2012

Comparative transcriptomic profiling of two tomato lines with different ascorbate content in the fruit.

Antonio Di Matteo, Adriana Sacco, Rosalba De Stefano, Luigi Frusciante, Amalia Barone

Open access · hybridAbstract readComparative Study
In one paragraph

Article in Biochemical genetics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Antonio Di MatteoDepartment of Soil, Plant, Environmental and Animal Sciences, University of Naples Federico II, Via Università 100, 80055, Portici, Italy.
Adriana Sacco
Rosalba De Stefano
Luigi Frusciante
Amalia Barone
University of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, interest in tomato breeding for enhanced antioxidant content has increased as medical research has pointed to human health benefits from antioxidant dietary intake. Ascorbate is one of the major antioxidants present in tomato, and little is known about mechanisms governing ascorbate pool size in this fruit. In order to provide further insights into genetic mechanisms controlling ascorbate biosynthesis and accumulation in tomato, we investigated the fruit transcriptome profile of the Solanum pennellii introgression line 10-1 that exhibits a lower fruit ascorbate level than its cultivated parental genotype. Our results showed that this reduced ascorbate level is associated with an increased antioxidant demand arising from an accelerated oxidative metabolism mainly involving mitochondria, peroxisomes, and cytoplasm. Candidate genes for controlling ascorbate level in tomato fruit were identified, highlighting the role of glycolysis, glyoxylate metabolism, and purine breakdown in modulating the ascorbate pool size.

Indexed as

AntioxidantsAscorbic AcidChromosome MappingCitric Acid CycleFruitGene Expression ProfilingGene Expression Regulation, PlantGenes, PlantGlycolysisGlyoxylatesOligonucleotide Array Sequence AnalysisOxidation-ReductionPeroxisomesPhenotypeQuantitative Trait LociSolanumAntioxidantsAscorbic AcidGlyoxylatesglyoxylic acid

Identifiers

PMID22911514
PMCPMC3493670
OpenAlexW2043198581

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.