ArticleEuropean radiology2013
Potentially relevant incidental findings on research whole-body MRI in the general adult population: frequencies and management.
Article in European radiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers, 5 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
78 citing papers in PubMed, 5 syntheses or guidelines pooled it, 152 citations in OpenAlex.
- Whole-body MRI for opportunistic cancer detection in asymptomatic individuals: a systematic review and meta-analysis.European radiology · 2026Pooled it
- Prevalence of incidental meningiomas and gliomas on MRI: a meta-analysis and meta-regression analysis.Acta neurochirurgica · 2021Pooled it
- Whole-body magnetic resonance imaging in children - how and why? A systematic review.Pediatric radiology · 2021Pooled it
- Whole-body MRI for preventive health screening: A systematic review of the literature.Journal of magnetic resonance imaging : JMRI · 2019Pooled it
- Potentially serious incidental findings on brain and body magnetic resonance imaging of apparently asymptomatic adults: systematic review and meta-analysis.BMJ (Clinical research ed.) · 2018Pooled it
- Communicating incidental and reportable findings from research MRIs: considering factors beyond the findings in an underrepresented pediatric population.BMC medical research methodology · 2021Trial
- Whole-body diffusion-weighted imaging: is it all we need for detecting metastases in melanoma patients?European radiology · 2013Trial
- The Diagnostic Yield of Whole-Body MRI as a Multi-disease Screening Modality: A Systematic Review and Meta-analysis.Journal of general internal medicine · 2026Article
- Incidental findings during pancreatic cyst surveillance: clinical relevance and implications for MRI protocol design.Abdominal radiology (New York) · 2026Article
- Agreement and Calibration Between FreeSurfer and Visually Quality-Controlled FSL/FAST-ALVIN Lateral Ventricle Volumetry in a Population-Based MRI Cohort.Brain sciences · 2026Article
- RADS classification systems for bone tumors: current status and where do we go from here?Cancer imaging : the official publication of the International Cancer Imaging Society · 2026Review
- How to implement a radiologist led whole-body MRI screening program.Radiology advances · 2026Review
- Von Hippel-Lindau Disease : A Comprehensive Review of Diagnosis, Genetics, Clinical Challenges, and Surveillance.Journal of Korean Neurosurgical Society · 2025Article
- A Protocol for Body MRI/CT and Extraction of Imaging-Derived Phenotypes (IDPs) from the China Phenobank Project.Phenomics (Cham, Switzerland) · 2024Article
- Trends in the incidence of newly diagnosed cerebral cavernous malformations in Finland: a population-based retrospective cohort study.The Lancet regional health. Europe · 2024Article
- Baseline MRI Examination in the NAKO Health Study—Findings on Feasibility, Participation and Dropout Rates, Comfort, and Image Quality.Deutsches Arzteblatt international · 2024Article
- Applying ONCO-RADS to whole-body MRI cancer screening in a retrospective cohort of asymptomatic individuals.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024Article
- [Patient-centered, value-based management of incidental findings in radiology].Radiologie (Heidelberg, Germany) · 2023Review
- Satisfaction of search awareness in trauma radiology: Malignant renal lesion on a trauma thoracolumbar spine CT.Radiology case reports · 2023Article
- The Spectrum of Solitary Benign Splenic Lesions-Imaging Clues for a Noninvasive Diagnosis.Diagnostics (Basel, Switzerland) · 2023Review
18 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo report the frequencies of potentially relevant incidental findings in the general adult population and to develop a protocol for their management in whole-body magnetic resonance imaging (wb-MRI).
methodsA total of 2,500 adult subjects (1,271 women, 1,229 men; mean age 53 years) from the population-based Study of Health in Pomerania underwent standardised wb-MRI. Additionally, 1,129 participants received contrast-enhanced cardiac MRI, 619 men received MR angiography and 544 women received MR mammography. Two independent residents performed first-line reading. A third reader resolved disagreements. An interdisciplinary advisory board decided about disclosure.
resultsThere were 1,330 incidental findings of potential clinical relevance in 904 subjects (36.2 %). Nine findings (0.4 %) required immediate referral. In total, 1,052 findings (79.1 %) were confirmed by the advisory board and disclosed to 787 participants (31.5 %). The abdominal organs (6.8 %), the urinary tract (6.8 %) and the skeletal system (6.0 %) were affected most often. While 383 findings (36.4 %) were indicated as benign and 62 (5.9 %) as malignant, most abnormalities, 607 (57.7 %), were of an unclear nature.
conclusionsPotentially relevant incidental findings are very common in wb-MRI research but the nature of these findings remains unclear in most cases. This requires dedicated management to protect subjects' welfare and research integrity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.