Evidence map›Paper›PMID 22911187›Full record

ArticleArchives of dermatology2012

The association between physical activity and the risk of incident psoriasis.

Hillary C Frankel, Jiali Han, Tricia Li, Abrar A Qureshi

Abstract read
In one paragraph

Article in Archives of dermatology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 4 pooled it
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 4 syntheses or guidelines pooled it, 71 citations in OpenAlex.

  1. Pooled it
  2. Lifestyle changes for treating psoriasis.The Cochrane database of systematic reviews · 2019
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Managing the Patient with Psoriasis and Metabolic Comorbidities.American journal of clinical dermatology · 2024
    Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Psoriasis and Exercise: A Review.Psoriasis (Auckland, N.Z.) · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Hillary C FrankelDepartment of Dermatology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.
Jiali Han
Tricia Li
Abrar A Qureshi
Harvard University Press · US

Funding

Risk Factors for Breast Cancer in Younger NursesR01CA050385 · NCI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI ELIASSEN, A. HEATHER, WILLETT, WALTER C. · 1989 to 2019
$32.3M
NCI NIH HHS CA50385NCI NIH HHS R01 CA050385
6 · The paper itself

Abstract

objectiveTo examine the association between total physical activity, walking, and vigorous exercise and the incidence of psoriasis in women.

designCohort study.

settingThe Nurses' Health Study II, a cohort of 116,430 women aged 27 to 44 years in 1991.

participantsThe study population included 86,655 US female nurses who reported whether they had ever been diagnosed as having psoriasis and who completed detailed physical activity questionnaires in 1991, 1997, and 2001. We excluded participants with a history of psoriasis prior to 1991.

main outcome measuresRisk of psoriasis by quintile of physical activity as measured by a metabolic equivalent task score.

resultsWe documented 1026 incident psoriasis cases during 1,195,703 person-years of follow-up (14 years, 1991-2005). After adjusting for age, smoking, and alcohol use, increasing physical activity was inversely associated with the risk of psoriasis. The most physically active quintile of women had a lower multivariate relative risk (RR) of psoriasis (0.72 [95% CI, 0.59-0.89; P < .001 for trend]) compared with the least active quintile. Vigorous physical activity (≥6 metabolic equivalents) was associated with a reduced risk of psoriasis (multivariate RR for the highest quintile, 0.66 [95% CI, 0.54-0.81; P < .001 for trend]); this association remained significant after adjusting for body mass index (RR, 0.73 [95% CI, 0.60-0.90; P = .009 for trend]). Walking was not associated with psoriasis risk. In a subset of 550 confirmed psoriasis cases, we observed a similarly reduced risk of psoriasis associated with vigorous physical activity (multivariate RR for the highest quintile, 0.64 [95% CI, 0.48-0.86; P = .03 for trend]).

conclusionIn this study of US women, vigorous physical activity is independently associated with a reduced risk of incident psoriasis.

Indexed as

AdultConfidence IntervalsExerciseFemaleHumansIncidenceMetabolic EquivalentMotor ActivityMultivariate AnalysisProportional Hazards ModelsPsoriasisRisk FactorsUnited StatesWalking

Identifiers

PMID22911187
PMCPMC4102422
OpenAlexW1978802083

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.