Evidence map›Paper›PMID 22911110›Full record

ArticleCancer prevention research (Philadelphia, Pa.)2012

Validation of LOH profiles for assessing oral cancer risk.

Mark W Lingen, Eva Szabo

Abstract readComment
In one paragraph

Article in Cancer prevention research (Philadelphia, Pa.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Mark W LingenDepartment of Pathology, The University of Chicago, 5841 South Maryland Ave, MC 6101, Chicago, IL 60637, USA. Mark.Lingen@uchospitals.edu
Eva Szabo

Funding

ORAL CANCER, RETINOIDS, AND ANTIANGIOGENESISR01DE012322 · NIDCR · UNIVERSITY OF CHICAGO · PI LINGEN, MARK W. · 1998 to 2009
$2.3M
NIDCR NIH HHS R01 DE012322
6 · The paper itself

Abstract

This perspective examines the report by Zhang and colleagues in this issue of the journal (beginning on page 1081) on the validation and refinement of a set of risk markers for oral premalignant lesion progression that incorporates loss of heterozygosity markers. The perspective also discusses some of the challenges and opportunities of incorporating predictive biomarkers into monitoring and refined enrollment criteria for prevention studies.

Indexed as

FemaleHumansLoss of HeterozygosityMaleMouth NeoplasmsPrecancerous Conditions

Identifiers

PMID22911110
PMCPMC3435466

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.