ArticleEuropean journal of clinical nutrition2012
Inflammatory markers and metabolic syndrome among adolescents.
Article in European journal of clinical nutrition, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- Leptin, CRP, and adiponectin correlate with body fat percentage in adolescents: systematic review and meta-analysis.Frontiers in nutrition · 2025Pooled it
- Epidemiological Impact of Metabolic Syndrome in Overweight and Obese European Children and Adolescents: A Systematic Literature Review.Nutrients · 2023Pooled it
- Inflammatory Biomarkers and Components of Metabolic Syndrome in Adolescents: a Systematic Review.Inflammation · 2022Pooled it
- Performance of anthropometric indicators as predictors of metabolic syndrome in Brazilian adolescents.BMC pediatrics · 2018Trial
- Environmental Radon Exposure and Inflammatory Responses in Children and Adolescents: Evidence from a High-Radon Region in Kazakhstan.Biomedicines · 2026Article
- Association of Three Novel Inflammatory Markers: Lymphocyte to HDL-C Ratio, High-Sensitivity C-Reactive Protein to HDL-C Ratio and High-Sensitivity C-Reactive Protein to Lymphocyte Ratio With Metabolic Syndrome.Endocrinology, diabetes & metabolism · 2024Article
- The sex-dependent response to psychosocial stress and ischaemic heart disease.Frontiers in cardiovascular medicine · 2023Review
- A visualized and scientometric analysis of research trends of weight loss in overweight/obese children and adolescents (1958-2021).Frontiers in public health · 2022Article
- Distinct Changes in Gut Microbiota Are Associated with Estradiol-Mediated Protection from Diet-Induced Obesity in Female Mice.Metabolites · 2021Article
- Relationship between triglyceride glucose index, retinopathy and nephropathy in Type 2 diabetes.Endocrinology, diabetes & metabolism · 2021Observational
- Oxidative Stress and Pro-Inflammatory Status in Patients with Non-Alcoholic Fatty Liver Disease.Antioxidants (Basel, Switzerland) · 2020Article
- Developmental trajectories of body mass index from childhood into late adolescence and subsequent late adolescence-young adulthood cardiometabolic risk markers.Cardiovascular diabetology · 2019Article
- A Data Mining Approach Identified Salivary Biomarkers That Discriminate between Two Obesity Measures.Journal of obesity · 2019Article
- Triglyceride glucose index for predicting cardiovascular outcomes in patients with coronary artery disease.Journal of thoracic disease · 2018Article
- Beverage Consumption among Adults in the Balearic Islands: Association with Total Water and Energy Intake.Nutrients · 2018Article
- Associations between metabolic syndrome components and markers of inflammation in Welsh school children.European journal of pediatrics · 2018Article
- Adiponectin and pro-inflammatory cytokines are modulated in Vietnamese patients with type 2 diabetes mellitus.Journal of diabetes investigation · 2017Article
- Quercetin Impacts Expression of Metabolism- and Obesity-Associated Genes in SGBS Adipocytes.Nutrients · 2016Article
- Association of complete blood cell counts with metabolic syndrome in an elderly population.BMC geriatrics · 2016Article
- Correlation of serum adiponectin and adiponectin gene polymorphism with metabolic syndrome in Chinese adolescents.European journal of clinical nutrition · 2015Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectivesThe alarming increase in obesity worldwide is of concern, owing to the associations of obesity with metabolic syndrome (MetS), which has been associated with a proinflammatory state characterized by elevated plasma concentrations of several markers of inflammation. The aim of this study was to assess levels of inflammatory markers and their association with MetS among adolescents. SUBJECTS/
methodsA random sample of adolescents (n=362, 143 boys and 219 girls, 12-17 years) was interviewed, anthropometrically measured and provided a fasting blood sample. Circulating levels of adiponectin, leptin, tumour necrosis factor-alpha, plasminogen activator inhibitor 1 (PAI-1), interleukin-6 and high-sensitivity C-reactive protein were measured. The association between inflammatory markers and sex, age, body mass index (BMI) status, MetS, physical activity and blood pressure was also calculated.
resultsAdiponectin levels are inversely associated and leptin levels are directly associated with MetS and BMI, but directly with gender (females show higher levels than boys), and PAI-1 levels are directly associated with MetS, among adolescents.
conclusionsLeptin, adiponectin and PAI-1 may be used as biomarkers to predict MetS among adolescents.
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