Evidence map›Paper›PMID 22909290›Full record

ArticleMaternal & child nutrition2014

Is breastfeeding related to bone properties? A longitudinal analysis of associations between breastfeeding duration and pQCT parameters in children and adolescents.

Tilman Kühn, Anja Kroke, Thomas Remer, Eckhard Schönau, Anette E Buyken

Abstract read
In one paragraph

Article in Maternal & child nutrition, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

5 authors.

Tilman KühnDepartment of Nutritional, Food and Consumer Sciences, University of Applied Sciences Fulda, Fulda, Germany; Department of Cancer Epidemiology, German Cancer Research Center - DKFZ, Heidelberg, Germany.
Anja Kroke
Thomas Remer
Eckhard Schönau
Anette E Buyken

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nutritive and bioactive components of human milk could be involved in programming metabolic systems that affect bone growth throughout the life course. Bone properties in childhood and adolescence might differ, depending on breastfeeding duration. Thus, breastfeeding could be a relevant factor in the context of primary osteoporosis prevention. The prospective association between breastfeeding duration and bone properties was investigated using the data of 284 participants of the Dortmund Nutritional and Anthropometric Longitudinally Designed Study. Breastfeeding duration was assessed during infancy. Bone properties were measured by peripheral quantitative computed tomography (pQCT) at ages 5-23 years. Cortical volumetric bone mineral density, cortical bone mineral content, strength strain index, total cross-sectional area of the bone and cross-sectional area of the cortical bone were determined at the 65% site of the radius. Linear regression analyses were performed to check for differences in pQCT parameters of subjects who had not or shortly been breastfed (0-16 weeks) and subjects who had been breastfed for a long duration (≥17 weeks). Multivariable models adjusted for age, gender, forearm length, muscle cross-sectional area, body mass index standard deviation score (SDS), height SDS and socio-economic status did not yield associations between breastfeeding duration and pQCT parameters. These findings suggest neither protective nor adverse effects of prolonged breastfeeding on bone health in childhood and adolescence. Influences of early nutrition on bone growth might be overridden by current effects of mechanical loads on bone physiology.

Indexed as

Bone DensityBreast FeedingAdolescentBody HeightBody Mass IndexBody WeightChildChild, PreschoolFemaleHumansLinear ModelsLongitudinal StudiesMaleMilk, HumanMultivariate AnalysisOsteoporosisbone growthbreastfeedingearly nutrition programmingpQCT

Identifiers

PMID22909290
PMCPMC6860239

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.