ArticleBMC ophthalmology2012
A comparison of the sensitivity of EQ-5D, SF-6D and TTO utility values to changes in vision and perceived visual function in patients with primary open-angle glaucoma.
Article in BMC ophthalmology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed, 62 citations in OpenAlex.
- Portable electronic vision enhancement systems in comparison with optical magnifiers for near vision activities: an economic evaluation alongside a randomized crossover trial.Acta ophthalmologica · 2017Trial
- Impact of Treatment with Naloxegol for Opioid-Induced Constipation on Patients' Health State Utility.Advances in therapy · 2016Trial
- Content Validity of Two Generic Preference-Based Measures in Retinitis Pigmentosa, Including X-Linked Retinitis Pigmentosa.PharmacoEconomics - open · 2026Article
- Emerging perspectives in quality of life after trabeculectomy surgery.Eye (London, England) · 2025Article
- Cost-effectiveness of the anti-vascular endothelial growth factor intravitreal injection and panretinal photocoagulation for patients with proliferative diabetic retinopathy in South Korea.BMC health services research · 2023Article
- Psychometric properties and comparison of four health utility approaches among myopia patients in China.Health and quality of life outcomes · 2023Article
- Quality of Life and Economic Impacts of Retinitis Pigmentosa on Japanese Patients: A Non-interventional Cross-sectional Study.Advances in therapy · 2023Article
- Predictors of problems reported on the EQ-5D-3L dimensions among people with impaired vision in northern Portugal.Health and quality of life outcomes · 2022Observational
- Cost-effectiveness of primary surgical versus primary medical management in the treatment of patients presenting with advanced glaucoma.The British journal of ophthalmology · 2022Article
- Patient-Reported Health-Related Quality of Life in Individuals with Inherited Retinal Diseases.Ophthalmology science · 2022Article
- Evaluating the Impact of Therapy on Quality of Life in Type 2 Diabetes: A Literature Review of Utilities Associated with Treatment-Related Attributes.Patient related outcome measures · 2022Review
- Utility Index and Patient-Reported Outcome Measures in Glaucomatous Patients Comparing with Normal Participants.Clinical ophthalmology (Auckland, N.Z.) · 2021Article
- Time Trade-off Utility Values in Noninfectious Uveitis.American journal of ophthalmology · 2019Article
- Lessons learned from the development and implementation of a patient-reported outcome and experience measure (POEM) in an Australian glaucoma practice.BMC ophthalmology · 2019Article
- Utility values for glaucoma patients in Korea.PloS one · 2018Article
- Multivariable Regression Model of the EuroQol 5-Dimension Questionnaire in Patients Seeking Outpatient Low Vision Rehabilitation.Ophthalmic epidemiology · 2017Observational
- Impact of Diabetic Retinopathy on Health-related Quality of Life in Iranian Diabetics.Iranian journal of public health · 2017Article
- Article
- Preference-based disease-specific health-related quality of life instrument for glaucoma: a mixed methods study protocol.BMJ open · 2016Article
- Response to: Comment on 'Cost effectiveness of collagen crosslinking for progressive keratoconus in the UK NHS'.Eye (London, England) · 2016Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEconomic viability of treatments for primary open-angle glaucoma (POAG) should be assessed objectively to prioritise health care interventions. This study aims to identify the methods for eliciting utility values (UVs) most sensitive to differences in visual field and visual functioning in patients with POAG. As a secondary objective, the dimensions of generic health-related and vision-related quality of life most affected by progressive vision loss will be identified.
methodsA total of 132 POAG patients were recruited. Three sets of utility values (EuroQoL EQ-5D, Short Form SF-6D, Time Trade Off) and a measure of perceived visual functioning from the National Eye Institute Visual Function Questionnaire (VFQ-25) were elicited during face-to-face interviews. The sensitivity of UVs to differences in the binocular visual field, visual acuity and visual functioning measures was analysed using non-parametric statistical methods.
resultsMedian utilities were similar across Integrated Visual Field score quartiles for EQ-5D (P = 0.08) whereas SF-6D and Time-Trade-Off UVs significantly decreased (p = 0.01 and p = 0.001, respectively). The VFQ-25 score varied across Integrated Visual Field and binocular visual acuity groups and was associated with all three UVs (P ≤ 0.001); most of its vision-specific sub-scales were associated with the vision markers. The most affected dimension was driving. A relationship with vision markers was found for the physical component of SF-36 and not for any dimension of EQ-5D.
conclusionsThe Time-Trade-Off was more sensitive than EQ-5D and SF-6D to changes in vision and visual functioning associated with glaucoma progression but could not measure quality of life changes in the mildest disease stages.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.