ArticleThe American journal of tropical medicine and hygiene2012
Epidemiology and molecular characterization of hepatitis B virus infection in isolated villages in the Western Brazilian Amazon.
Article in The American journal of tropical medicine and hygiene, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The trial behind it
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Who cites it
10 citing papers in PubMed, 28 citations in OpenAlex.
- Article
- Hepatitis B Virus and Delta Infection: Special Considerations in the Indigenous and Isolated Riverside Populations in the Amazon Region.Clinical liver disease · 2020Review
- Determination of hepatitis B, C and D prevalence among urban and Amerindian populations from the Eastern Brazilian Amazon: a cross sectional study.BMC infectious diseases · 2018Article
- Phylogenetic analysis and genotype distribution of Hepatitis B Virus (HBV) in Roraima, Brazil.Revista do Instituto de Medicina Tropical de Sao Paulo · 2018Article
- Screening for hepatitis D and PEG-Interferon over Tenofovir enhance general hepatitis control efforts in Brazil.PloS one · 2018Article
- Hepatitis B virus burden in developing countries.World journal of gastroenterology · 2015Review
- The Seroprevalence of Hepatitis B in Akbar Abad Village, Kavar, Southern Iran.International journal of preventive medicine · 2014Article
- Occult hepatitis B virus infection among blood donors from the Brazilian Amazon: implications for transfusion policy.Vox sanguinis · 2014Article
- Enigmatic origin of hepatitis B virus: an ancient travelling companion or a recent encounter?World journal of gastroenterology · 2014Review
- Phylogeography and evolutionary history of hepatitis B virus genotype F in Brazil.Virology journal · 2013Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Individuals from three isolated, rural communities in the western Brazilian Amazon were evaluated for serological markers of hepatitis B virus (HBV) infection, HBV genotype, and the presence of risk factors for infection and transmission. Of the 225 individuals studied, 79.1% had serological evidence of HBV infection; 10.2% individuals were chronic carriers for HBV surface antigen (HBsAg-positive). Analysis of risk factors indicates that HBV is transmitted mainly horizontally within the family from a chronic "active" carrier for hepatitis B "e" antigen (HBeAg-positive), though a strong possibility of vertical transmission remains. The predominance of HBV genotype F, with a higher genomic similarity between the isolates, indicated a relatively recent introduction of HBV, from a common source, to the area. This study sheds light on the HBV epidemiology in the Brazilian Amazon region and highlights the need for greater emphasis on HBV control and immunization programs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.