SynthesisInternational journal of colorectal disease2012
External coating of colonic anastomoses: a systematic review.
Synthesis in International journal of colorectal disease, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- A systematic review on the use of topical hemostats in trauma and emergency surgery.BMC surgery · 2018Pooled it
- Pharmacological interventions for improved colonic anastomotic healing: a meta-analysis.World journal of gastroenterology · 2014Pooled it
- Suture reinforcement using a modified cyanoacrylate glue to prevent anastomotic leak in colorectal surgery: a prospective multicentre randomized trial : The Rectal Anastomotic seaL (ReAL) trial.Techniques in coloproctology · 2024Trial
- Hemopatch serosal reinforcement in right colectomy: transforming anastomotic leak patterns and severity compared to second-line suture technique-a 10-Year Retrospective Cohort Study of 352 patients.Updates in surgery · 2026Article
- Poly-ϵ-caprolactone scaffold as staple-line reinforcement of rectal anastomosis: an experimental piglet study.BMC gastroenterology · 2024Article
- The role of tissue adhesives and sealants in colorectal anastomotic healing-a scoping review.International journal of colorectal disease · 2023Article
- Novel external reinforcement device for gastrointestinal anastomosis in an experimental study.BMC surgery · 2023Article
- Anastomotic Considerations in Diverticulitis.Clinics in colon and rectal surgery · 2023Review
- Coating of Intestinal Anastomoses for Prevention of Postoperative Leakage: A Systematic Review and Meta-Analysis.Frontiers in surgery · 2022Review
- New Technologies to Prevent Anastomotic Leak.Clinics in colon and rectal surgery · 2021Review
- Fibrin Sealant: The Only Approved Hemostat, Sealant, and Adhesive-a Laboratory and Clinical Perspective.ISRN surgery · 2014Review
- Multilayered Human Skeletal Muscle Myoblast Sheets Promote the Healing Process After Colonic Anastomosis in Rats.Cell transplantationArticle
- Decreased leakage rate of colonic anastomoses by tachosil coating: an experimental study.International surgeryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeColon anastomotic leakage remains both a frequent and serious complication in gastrointestinal surgery. External coating of colonic anastomoses has been proposed as a means to lower the rate of this complication. The aim of this review was to evaluate existing studies on external coating of colonic anastomoses.
methodsCINAHL, EMBASE, and PubMed were searched up to September 2011 to identify studies evaluating external coating of colonic anastomoses.
resultsForty studies have evaluated 20 different coating materials, of which only fibrin sealant, omental pedicle graft, and hyaluronic acid/carboxymethylcellulose have been used in humans. Fibrin sealant has shown positive, however not significant, results. Omental pedicle graft can be used safely, yet without beneficial effects, whereas hyaluronic acid/carboxymethylcellulose should be avoided due to increased complications. The remaining coating materials have solely been evaluated in experimental animals with many contradictory and few positive results.
conclusionsExternal coating of colonic anastomoses has yet failed to show convincing results. Randomized clinical trials and high-quality experimental studies are warranted to determine the role of fibrin sealant, omental pedicle graft, and other coating materials for prevention of colon anastomotic leakage.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.