ArticleCardiovascular journal of Africa2012
Echocardiographic patterns in treatment-naïve HIV-positive patients in Lagos, south-west Nigeria.
Article in Cardiovascular journal of Africa, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 28 citations in OpenAlex.
- Prevalence and patterns of echocardiographic abnormalities among people living with HIV on anti-retroviral therapy in Kumasi, Ghana.BMC cardiovascular disorders · 2024Article
- Multimodality Imaging in HIV-Associated Cardiovascular Complications: A Comprehensive Review.International journal of environmental research and public health · 2023Review
- Article
- Diastolic dysfunction in people with HIV without known cardiovascular risk factors in Western Kenya.Open heart · 2022Article
- Cardiac Abnormalities of People Living with HIV: A Comparative Study Between HAART Experience and Treatment Naïve Groups in Ghana.International journal of general medicine · 2022Article
- Pulmonary hypertension in the developing world: Local registries, challenges, and ways to move forward.Global cardiology science & practice · 2020Article
- High prevalence of echocardiographic abnormalities in older HIV-infected children taking antiretroviral therapy.AIDS (London, England) · 2018Article
- The Use of First Line Highly Active Anti-Retroviral Therapy (HAART) is Not Associated with Qtc Prolongation in HIV Patients.Ethiopian journal of health sciences · 2017Article
- Cardiovascular Complications of HIV in Endemic Countries.Current cardiology reports · 2016Review
- International Congress of Drug Therapy in HIV Infection 23-26 October 2016, Glasgow, UK.Journal of the International AIDS Society · 2016Article
- Human Immunodeficiency Virus and Heart Failure in Low- and Middle-Income Countries.JACC. Heart failure · 2015Review
- Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionCardiovascular abnormalities are common in HIV-infected patients, although often clinically quiescent. This study sought to identify by echocardiography early abnormalities in treatment-naïve patients.
methodsOne hundred patients and 50 controls with no known traditional risk factors for cardiovascular disease were recruited for the study. The cases and controls were matched for age, gender and body mass index. Both groups had clinical and echocardiographic evaluation for cardiac abnormalities, and CD4 count was measured in all patients.
resultsThe cases comprised 57 females (57.0%) and 43 males (43.0%), while the controls were 28 females (56.0%) and 22 males (44.0%) (χ(2) = 0.01; p = 0.913). The mean age of the cases was 33.2 ± 7.7, while that of the controls was 31.7 ± 9.7 (t = 1.02; p = 0.31). Echocardiographic abnormalities were significantly more common in the cases than the controls (78 vs 16%; p = 0.000), including systolic dysfunction (30 vs 8%; p = 0.024) and diastolic dysfunction (32 vs 8%; p = 0.002). Other abnormalities noted in the cases were pericardial effusion in 47% (χ(2) = 32.10; p = 0.000) and dilated cardiomyopathy in 5% (five); none of the controls had either complication. One patient each had aortic root dilatation, mitral valve prolapse and isolated right heart dilatation and dysfunction.
conclusionCardiac abnormalities are more common in HIV-infected people than in normal controls. A careful initial and periodic cardiac evaluation to detect early involvement of the heart in the HIV disease is recommended.
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