Evidence map›Paper›PMID 22906945›Full record

ArticleHuman vaccines & immunotherapeutics2012

Vaccines against Toxoplasma gondii: status, challenges and future directions.

Qi Liu, Lachhman Das Singla, Huaiyu Zhou

Abstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. The Search for Drugs Derived from Natural Products forCurrent topics in medicinal chemistry · 2024
    Pooled it
  2. Live-attenuatedVirulence · 2026
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  7. Review
  8. The Development of TIM-Barrel Based Multi-Epitope Protein forAnimals : an open access journal from MDPI · 2025
    Article
  9. MIC13 ofJournal of parasitology research · 2025
    Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Public health challenges · 2023
    Article
  15. Article
  16. Toxoplasma gondii vaccine candidates: a concise review.Irish journal of medical science · 2023
    Review
  17. Article
  18. Mining the Proteome ofAnimals : an open access journal from MDPI · 2022
    Review
  19. Nano vaccines forFrontiers in immunology · 2022
    Article
  20. Clinical validation of visual LAMP and qLAMP assays for the rapid detection ofFrontiers in cellular and infection microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Qi LiuDepartment of Parasitology, Shandong University School of Medicine, Jinan, Shandong, China.
Lachhman Das Singla
Huaiyu Zhou

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Toxoplasma gondii is a ubiquitous protozoan parasite that can infect a wide range of animals including humans. This single known species in the genus Toxoplasma is considered as one of the most successful eukaryotic pathogens which is of major medical and veterinary importance. Effective vaccines may contribute toward preventing and controlling the spread of toxoplasmosis. The present communication addresses the current status of development of vaccines against T. gondii. Further discussion is made on the difficulties along with challenges, such as vaccine construct, mode of vaccine administration and standardization of immunization evaluation. Finally suggestions are made on possible directions for future research on the development of vaccines against T. gondii.

Indexed as

AnimalsHumansProtozoan VaccinesToxoplasmaToxoplasmosisProtozoan Vaccines

Identifiers

PMID22906945
PMCPMC3579912

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.