ArticleBMC pediatrics2012
Sex differences in response to maximal exercise stress test in trained adolescents.
Article in BMC pediatrics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 30 citations in OpenAlex.
- Fluid type influences acute hydration and muscle performance recovery in human subjects.Journal of the International Society of Sports Nutrition · 2019Trial
- Sex Differences in the Impact of Body Composition and Bone Mineral Content on Cardiopulmonary Performance in Elite Youth Water Polo Athletes.Sports (Basel, Switzerland) · 2026Article
- New applications of cardiopulmonary exercise testing parameters characterize age-related changes in exercise performance during adolescence.Frontiers in cardiovascular medicine · 2026Article
- Cardiopulmonary parameters in patients with Tetralogy of Fallot: the reference values for treadmill and cycle ergometer.Frontiers in cardiovascular medicine · 2026Article
- Energy System Contributions in Repeated Sprint Tests: Protocol and Sex Comparison.Journal of human kinetics · 2024Article
- Influence of physical fitness and weight status on autonomic cardiac modulation in children.Pediatric research · 2023Article
- Comprehensive cardiac evaluation to maximal exercise in a contemporary population of prepubertal children.Pediatric research · 2022Article
- A Combined Analysis of Peak and Submaximal Exercise Parameters in Delineating Underlying Mechanisms of Sex Differences in Healthy Adolescents.Pediatric cardiology · 2022Article
- Deconditioning does not explain orthostatic intolerance in ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome).Journal of translational medicine · 2021Article
- Validation of the Severity of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome by Other Measures than History: Activity Bracelet, Cardiopulmonary Exercise Testing and a Validated Activity Questionnaire: SF-36.Healthcare (Basel, Switzerland) · 2020Article
- Do women reduce the gap to men in ultra-marathon running?SpringerPlus · 2016Article
- Analysis of sex differences in open-water ultra-distance swimming performances in the FINA World Cup races in 5 km, 10 km and 25 km from 2000 to 2012.BMC sports science, medicine & rehabilitation · 2014Article
- Gender differences in myocardial function and arterio-ventricular coupling in response to maximal exercise in adolescent floor-ball players.BMC sports science, medicine & rehabilitation · 2014Article
- Muscle oxygen utilization and ventilatory parameters during exercise in people with cystic fibrosis: Role of HbAChronic respiratory diseaseArticle
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSex comparisons between girls and boys in response to exercise in trained adolescents are missing and we investigated similarities and differences as a basis for clinical interpretation and guidance.
methodsA total of 24 adolescent females and 27 adolescent males aged 13-19 years underwent a maximal bicycle exercise stress test with measurement of cardiovascular variables, cardiac output, lung volumes, metabolic factors/lactate concentrations and breath-by-breath monitoring of ventilation, and determination of peak VO(2).
resultsMaximum heart rate was similar in females (191 ± 9 bpm) and males (194 ± 7 bpm), cardiac index at maximum exercise was lower in females (7.0 ± 1.0 l/min/m(2)) than in males (8.3 ± 1.4 l/min/m(2), P < 0.05). Metabolic responses and RQ at maximum exercise were similar (females: 1.04 ± 0.06 vs. males: 1.05 ± 0.05). Peak VO(2) was lower in females (2.37 ± 0.34 l/min) than in males (3.38 ± 0.49 l/min, P < 0.05). When peak VO(2) was normalized to leg muscle mass sex differences disappeared (females: 161 ± 21 ml/min/kg vs. males: 170 ± 23 ml/min/kg). The increase in cardiac index during exercise is the key factor responsible for the greater peak VO(2) in adolescent boys compared to girls.
conclusionsDifferences in peak VO(2) in adolescent boys and girls disappear when peak VO(2) is normalized to estimated leg muscle mass and therefore provide a tool to conduct individual and intersex comparisons of fitness when evaluating adolescent athletes in aerobic sports.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.