Evidence map›Paper›PMID 22905903›Full record

ArticleJournal of medical primatology2012

The effect of season on inflammatory response in captive baboons.

Dianne McFarlane, Roman F Wolf, Kristen A McDaniel, Gary L White

Abstract read
In one paragraph

Article in Journal of medical primatology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.2field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Roles of cytokines in modulatingFrontiers in parasitology · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Dianne McFarlaneDepartment of Physiological Sciences, Center of Veterinary Health Sciences, Oklahoma State University, Stillwater, OK, USA. diannem@okstate.edu
Roman F Wolf
Kristen A McDaniel
Gary L White
Oklahoma State University · USUniversity of Oklahoma Health Sciences Center · US

Funding

CORE--BABOON RESEARCH RESOURCE PROGRAMP40RR012317 · NCRR · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI WHITE, GARY L · 1998 to 2011
$13.0M
DEVELOPMENT OF AN SPF BABOON COLONYR24RR016556 · NCRR · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI WHITE, GARY L · 2002 to 2011
$5.8M
Initiating factors of neurodegenerationK01RR023946 · NCRR · OKLAHOMA STATE UNIVERSITY STILLWATER · PI MCFARLANE, DIANNE · 2007 to 2011
$647k
NCRR NIH HHS K01 RR023946NCRR NIH HHS P40 RR012317NCRR NIH HHS P40 RR12317NCRR NIH HHS R24 RR016556NCRR NIH HHS R24 RR16556
6 · The paper itself

Abstract

introductionHighly seasonal animals demonstrate predictable changes in immune function that coincide with changes in photoperiod. Little is known about the effect of season on immune response in baboons. The objective of this study was to determine the effect of season on inflammatory response in baboons. MATERIALS AND

methodsPeripheral blood mononuclear cell cytokine response following immune stimulation and serum markers of inflammation were assessed during each season in two groups of young male baboons: one housed under natural light and one in a controlled environment of 12 hours light:12 hours dark.

resultsA seasonal immune rhythm was evident in both groups, with a greater TNF-α and IL-6 response to stimulation and serum CRP concentration in June and September compared with December.

conclusionsSeason is an important experimental confounder, and therefore, time of year should be controlled when designing studies and analyzing data from immune studies in baboons.

Indexed as

SeasonsAnimalsC-Reactive ProteinInflammationInterleukin-6Leukocytes, MononuclearMaleMonkey DiseasesPapioPhotoperiodTumor Necrosis Factor-alphaC-Reactive ProteinInterleukin-6Tumor Necrosis Factor-alpha

Identifiers

PMID22905903
PMCPMC3492523
OpenAlexW1973644625

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.